Body size and blood pressure: an analysis of Africans and the African diaspora

Simple item page
dc.contributor.authorCappuccio, F.P.
dc.contributor.authorKerry, S.M.
dc.contributor.authorAdeyemo, A.
dc.contributor.authorLuke, A.
dc.contributor.authorAmoah, A.G.
dc.contributor.authorBovet, P.
dc.contributor.authorConnor, M.D.
dc.contributor.authorForrester, T.
dc.contributor.authorGervasoni, J.P.
dc.contributor.authorKaki, G.K.
dc.contributor.authorPlange-Rhule, J.
dc.contributor.authorThorogood, M.
dc.contributor.authorCooper, R.S.
dc.date.accessioned2013-06-26T18:43:52Z
dc.date.accessioned2017-10-19T11:58:23Z
dc.date.available2013-06-26T18:43:52Z
dc.date.available2017-10-19T11:58:23Z
dc.date.issued2008-01
dc.description.abstractBACKGROUND: Blood pressure is directly and causally associated with body mass index (BMI) in populations worldwide. However, the relationship may vary across BMI in populations of African origin. METHODS: We compared the relationship between blood pressure and BMI in populations of African origin, using 13 samples from Africa, the Caribbean, the United Kingdom and the United States. We had access to data from individual participants for age, height, weight, blood pressure, and treatment of hypertension. Analysis was restricted to 18,072 participants (age 35-64 years; 44% men). We carried out multivariate regression analysis to estimate the relationship between blood pressure and BMI by country and by sex. The use of antihypertensive treatment was taken into account by exclusion and by sensitivity analysis. RESULTS: There was a positive relationship between both systolic and diastolic blood pressure and BMI. In men the slopes for systolic blood pressure varied from 0.27 mm Hg per kg/m (95% confidence interval = -0.01 to 0.56) in the United States to 1.72 mm Hg per kg/m (95% confidence interval = 0.92 to 2.53) in Ghana (Kumasi). In women, the slopes varied from 0.08 (-0.54 to 0.72) in South Africa to 1.32 (0.98 to 1.66) in the Republic of Congo. Similar variation in trends was seen for diastolic blood pressure. The higher the BMI, the shallower the slopes [-0.10 (-0.15 to -0.06) for systolic, -0.09 (-0.12 to -0.06) for diastolic]. No differences were seen after excluding persons who were being treated for hypertension. CONCLUSIONS: Blood pressure and BMI levels vary among populations of the African diaspora. The effect of BMI on blood pressure levels diminishes as BMI increases. These results suggest a complex relationship among excess body weight, adiposity, and energy expenditure.en_US
dc.identifier.citationCappuccio, F. P., Kerry, S. M., Adeyemo, A., Luke, A., Amoah, A. G., Bovet. P., Connor, M. D, Forrester, T., . . . Cooper, R. S. (2008). Body size and blood pressure: an analysis of Africans and the African diaspora. Epidemiology, 19(1), 38-46. Link to full text: http://hinari-gw.who.int/whalecomwww.ncbi.nlm.nih.gov/whalecom0/pmc/articles/PMC2830114/en_US
dc.identifier.issn10443983
dc.identifier.urihttp://197.255.68.203/handle/123456789/4206
dc.language.isoenen_US
dc.publisherEpidemiologyen_US
dc.subjectAdulten_US
dc.subjectAfrican Continental Ancestry Groupen_US
dc.subjectBlood Pressureen_US
dc.subjectBody Mass Indexen_US
dc.subjectFemaleen_US
dc.subjectHumansen_US
dc.subjectHypertensionen_US
dc.subjectMaleen_US
dc.subjectMiddle Ageden_US
dc.subjectObesityen_US
dc.subjectRegression Analysisen_US
dc.titleBody size and blood pressure: an analysis of Africans and the African diasporaen_US
dc.typeArticleen_US

Files

License bundle
Now showing 1 - 2 of 2
No Thumbnail Available
Name:
license.txt
Size:
1.82 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
No Thumbnail Available
Name:
license.txt
Size:
0 B
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

Department of Medical Biochemistry