Highly multiplexed genotyping of thiopurine S-methyltransferase variants using MALDI-TOF mass spectrometry: reliable genotype in different ethnic groups
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Date
Authors
Asante-Poku, S.
Elke Schaeffeler, E.
Ulrich, M.
Zanger, S.
Jae-Gook, S.
Schwab, M.
Journal Title
Journal ISSN
Volume Title
Publisher
Clinical Chemistry (54): 1637-1647
Abstract
To avoid severe hematotoxicity in patients, determination of the TPMT (thiopurine S-methyltransferase) genotype before commencing thiopurine therapy has become accepted.