Longitudinal control of blood pressure among a cohort of Ghanaians with hypertension: A multicenter, hospital-based study

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dc.contributor.authorOfori-Adjei, D.
dc.contributor.authorSarfo, F.S.
dc.contributor.authorMobula, L.
dc.contributor.authorPlange-Rhule, J.
dc.contributor.authorGebregziabher, M.
dc.contributor.authorAnsong, D.
dc.contributor.authorSarfo-Kantanka, O.
dc.contributor.authorArthur, L.
dc.contributor.authorSablah, J.
dc.contributor.authorGavor, E.
dc.contributor.authorBurnham, G.
dc.contributor.authorOfori-Adjei, D.
dc.date.accessioned2020-06-30T11:53:53Z
dc.date.available2020-06-30T11:53:53Z
dc.date.issued2020-03-04
dc.descriptionResearch Articleen_US
dc.description.abstractThere are limited data on factors associated with longitudinal control of blood pressure (BP) among Ghanaians on antihypertensive treatment. We sought to evaluate associations between prospective BP control and 24 putative factors within socio-demographic, biological, and organizational domains. This is a cohort study involving 1867 (65%) adults with hypertension and 1006 (35%) with both hypertension and diabetes mellitus at five public hospitals. Clinic BP was measured every 2 months for 18 months of follow-up. A multivariate logistic regression analysis was fitted via generalized linear mixed models to identify factors associated with clinic BP ≥ 140/90 mm Hg at each clinic visit during follow-up. Mean age of study participants was 58.9 ± 16.6 years and 76.8% were females. Proportions with controlled BP increased from 46.3% at baseline to 59.8% at month 18, P < .0001. Eight factors with adjusted OR (95% CI) associated prospectively with uncontrolled BP were male gender: 1.37 (1.09-1.72), secondary education: 1.32 (1.00-1.74), non-adherence to antihypertensive treatment: 1.03 (1.00-1.06), fruit intake: 0.94 (0.89-1.00), duration of hypertension diagnosis: 1.01 (1.00-1.02), hypertension with diabetes mellitus: 2.05 (1.72-2.46), number of antihypertensive medications: 1.63 (1.49-1.79), and estimated glomerular filtration rate (mL/min rise): 0.82 (0.76-0.89). Interventions aimed at addressing modifiable factors associated with poorly controlled BP would be critical in prevention of cardiovascular diseases among Ghanaiansen_US
dc.description.sponsorshipFunding for this study was provided by MSD, Novartis, Pfizer, Sanofi and the Bill and Melinda Gates Foundation (collectively, the Funders) through the New Venture Fund (NVF).en_US
dc.identifier.citationSarfo FS, Mobula L, Plange-Rhule J, et al. Longitudinal control of blood pressure among a cohort of Ghanaians with hypertension: A multicenter, hospital-based study. J Clin Hypertens. 2020;22:949–958. https://doi. org/10.1111/jch.13873en_US
dc.identifier.otherhttps://doi. org/10.1111/jch.13873
dc.identifier.urihttp://ugspace.ug.edu.gh/handle/123456789/35400
dc.language.isoenen_US
dc.publisherJournal of Clinical Hypertensionen_US
dc.relation.ispartofseries22;949-958
dc.subjectblood pressure (BP)en_US
dc.subjecthypertensionen_US
dc.subjectsecondary educationen_US
dc.subjectClinic BPen_US
dc.titleLongitudinal control of blood pressure among a cohort of Ghanaians with hypertension: A multicenter, hospital-based studyen_US
dc.typeArticleen_US

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