Co-Designing And Pilot Testing A Digital Game To Improve Vaccine Attitudes And Misinformation Resistance In Ghana.
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Human Vaccines & Immunotherapeutics
Abstract
Misinformation related to vaccines has been shown to potentially negatively impact public perceptions
and intentions to vaccinate in many contexts including COVID-19 vaccination in Ghana. Psychological
inoculation – where recipients are warned about the misleading techniques used in misinformation – is
a potential intervention which could preemptively boost public resistance against misinformation. Cranky
Uncle Vaccine is an interactive, digital game that applies inoculation, offering a scalable tool building
public resilience against vaccine misinformation and promoting positive health-related behaviors. In this
study, we document the process of developing and testing a West African version of Cranky Uncle
Vaccine, with co-design workshops and a pilot test conducted in urban and peri-urban areas of the
Greater Accra region of Ghana with 829 young people who had access to mobile and computer devices.
The average age was 21.8 and participants were highly educated (median education level “Some/all
university”) with slightly more females (51.2%) than males (48.4%). Pilot participants filled out surveys
before and after playing the game, measuring vaccine attitudes (pre-game M = 3.4, post-game M = 3.6),
intent to get vaccinated (pre-game M = 3.5, post-game M = 3.6), and discernment between vaccine facts
and fallacies (pre-game AUC = 0.72, post-game AUC = 0.75). We observed a significant improvement in
attitudes toward vaccines, with players demonstrating increased likelihood to get vaccinated after
completing the game. Among players who indicated that they were unlikely to get vaccinated in the pregame survey (N = 52, or 6.3% of participants), just over half of these participants (53%) switched to likely
to get vaccinated after playing the game. Perceived reliability of vaccine facts remained the same, while
perceived reliability of vaccine fallacies significantly decreased, indicating improved ability to spot
misleading arguments about vaccines. These results demonstrate the effectiveness of a digital game in
building public resilience against vaccine misinformation as well as improving vaccine attitudes and
intent to get vaccinated.
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Cook, J., Lepage, C., Hopkins, K. L., Cook, W., Kolog, E. A., Thomson, A., ... & Burnette, S. (2024). Co-designing and pilot testing a digital game to improve vaccine attitudes and misinformation resistance in Ghana. Human Vaccines & Immunotherapeutics, 20(1), 2407204.
