evaluation of vigabatrin as monotherapy in newly diagnosed partial seizures in childhood.
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Perniola, T.
Spina, A.
Margari, L.
Losito, R.
Marzocco, P.L.
Bello, A.
Zizzo, L.
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Abstract
Fifty-three childreen with newly diagnosed partial epilepsies received GVG monotherapy (mean 44/mg/kg/day). After a mean follow up time of 16,5 months, 26 childreen (49%) were seazures-free, 18 (33,9%) had a decrease in seizure frequency and 9 childreen (16,9%) had unchanged seizure frequency. Side effects were reported in 22 childreen (41,5%) and included weight gain, increased appetite and restlessness.
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Perniola, T., Spina, A., Margari, L., Losito, R., Marzocco, P. L., Bello, A., . . . Zizzo, L. (1997). Open evaluation of vigabatrin as monotherapy in newly diagnosed partial seizures in childhood. [Monoterapia con vigabatrin nell'epilessia parziale di nuova diagnosi in eta evolutiva: Valutazione in aperto dell' efficacia e della tollerabilita] Bollettino - Lega Italiana Contro l'Epilessia, (99), 141-143.