Impact of blood perilipin A levels on obesity and metabolic health

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dc.contributor.authorOfori, E.K.
dc.contributor.authorLetsu, B.S.
dc.contributor.authorAmponsah, S.K.
dc.contributor.authorAhenkorah, J.
dc.contributor.authorCrabbe, S.
dc.contributor.authorKwao‑Zigah, G.
dc.contributor.authorOppong, S.Y.
dc.contributor.authorDiaba‑Nuhoho, P.
dc.contributor.authorAmanquah, S.D.
dc.date.accessioned2023-01-25T15:25:39Z
dc.date.available2023-01-25T15:25:39Z
dc.date.issued2022
dc.descriptionResearch Articleen_US
dc.description.abstractObjective: Perilipin A is a common protein that coats lipid surfaces preventing them from being exposed to oxida‑ tive damage. Researchers have found little consistency in the relationship between perilipin A levels in the blood and body fat. This study was a cross-sectional observational that looked at circulating perilipin A levels and how they relate to metabolic health. Results: The participants in this study were 86 individuals with a mean age of 45.5±1.2 years. Multiple clinical and metabolic indicators (age, weight, BMI, total body fat mass, triglyceride, and HOMA-IR) were shown to be inversely associated with perilipin A levels (rho=− 0.32, − 0.37, − 0.40, − 0.45, − 0.33 and − 0.29; p<0.05 respectively). Obese persons were almost six times more likely than non-obese individuals to have lower perilipin A levels (odds ratio=6.22, CI=2.35–11.50, p<0.001). Our fndings underscore the important role of perilipin A proteins in metabolic health. Keyworden_US
dc.identifier.otherhttps://doi.org/10.1186/s13104-022-06261-3
dc.identifier.urihttp://ugspace.ug.edu.gh:8080/handle/123456789/38500
dc.language.isoenen_US
dc.publisher. BMC Research Notesen_US
dc.subjectPerilipin Aen_US
dc.subjectObesityen_US
dc.subjectInsulin resistanceen_US
dc.subjectLipidsen_US
dc.titleImpact of blood perilipin A levels on obesity and metabolic healthen_US
dc.typeArticleen_US

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