Impact of blood perilipin A levels on obesity and metabolic health
dc.contributor.author | Ofori, E.K. | |
dc.contributor.author | Letsu, B.S. | |
dc.contributor.author | Amponsah, S.K. | |
dc.contributor.author | Ahenkorah, J. | |
dc.contributor.author | Crabbe, S. | |
dc.contributor.author | Kwao‑Zigah, G. | |
dc.contributor.author | Oppong, S.Y. | |
dc.contributor.author | Diaba‑Nuhoho, P. | |
dc.contributor.author | Amanquah, S.D. | |
dc.date.accessioned | 2023-01-25T15:25:39Z | |
dc.date.available | 2023-01-25T15:25:39Z | |
dc.date.issued | 2022 | |
dc.description | Research Article | en_US |
dc.description.abstract | Objective: Perilipin A is a common protein that coats lipid surfaces preventing them from being exposed to oxida‑ tive damage. Researchers have found little consistency in the relationship between perilipin A levels in the blood and body fat. This study was a cross-sectional observational that looked at circulating perilipin A levels and how they relate to metabolic health. Results: The participants in this study were 86 individuals with a mean age of 45.5±1.2 years. Multiple clinical and metabolic indicators (age, weight, BMI, total body fat mass, triglyceride, and HOMA-IR) were shown to be inversely associated with perilipin A levels (rho=− 0.32, − 0.37, − 0.40, − 0.45, − 0.33 and − 0.29; p<0.05 respectively). Obese persons were almost six times more likely than non-obese individuals to have lower perilipin A levels (odds ratio=6.22, CI=2.35–11.50, p<0.001). Our fndings underscore the important role of perilipin A proteins in metabolic health. Keyword | en_US |
dc.identifier.other | https://doi.org/10.1186/s13104-022-06261-3 | |
dc.identifier.uri | http://ugspace.ug.edu.gh:8080/handle/123456789/38500 | |
dc.language.iso | en | en_US |
dc.publisher | . BMC Research Notes | en_US |
dc.subject | Perilipin A | en_US |
dc.subject | Obesity | en_US |
dc.subject | Insulin resistance | en_US |
dc.subject | Lipids | en_US |
dc.title | Impact of blood perilipin A levels on obesity and metabolic health | en_US |
dc.type | Article | en_US |
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