Vitreomacular interface abnormalities in the Ghanaian African
dc.contributor.author | Amoaku, W.M. | |
dc.contributor.author | Cushley, L. | |
dc.contributor.author | Akafo, S. | |
dc.contributor.author | et al. | |
dc.date.accessioned | 2023-10-19T10:59:38Z | |
dc.date.available | 2023-10-19T10:59:38Z | |
dc.date.issued | 2023 | |
dc.description | Research Article | en_US |
dc.description.abstract | BACKGROUND/OBJECTIVE: Describe vitreomacular interface abnormalities (VMIA) using spectral-domain optical coherence tomography (SD-OCT), and correlations with age-related macular degeneration (AMD) grade in Ghanaian Africans. SUBJECTS/METHODS: Prospective, cross-sectional study of adults aged ≥50 years recruited in Ghana AMD Study. Participant demographics, medical histories, ophthalmic examination, digital colour fundus photography (CFP) were obtained. High resolution fve-line raster OCT, Macular Cube 512 × 128 scans, and additional line scans in areas of clinical abnormality, were acquired. SD-OCT VMI features classifed by International Vitreomacular Traction Study Group system and relationships to AMD grade were evaluated. Outcomes: VMIA prevalence, posterior vitreous detachment (PVD), vitreomacular adhesions (VMA), vitreomacular traction (VMT), epiretinal membranes (ERM), correlations with AMD grade. RESULTS: The full Ghana AMD cohort included 718 participants; 624 participants (1248 eyes) aged ≥50 years (range = 50–101, mean = 68.8), 68.9% female were included in this analysis. CFP with OCT scans were available for 776 eyes (397 participants); 707 (91.1%) had gradable CFP and OCT scans for both AMD and VMI grading forming the dataset for this report. PVD was absent in 504 (71.3%); partial and complete PVD occurred in 16.7% and 12.0% respectively. PVD did not increase with age (p = 0.720). VMIA without traction and macular holes were observed in 12.2% of eyes; 87.8% had no abnormalities. VMIA was not signifcantly correlated with AMD grade (p = 0.819). CONCLUSIONS: This provides the frst assessment of VMIA in Ghanaian Africans. VMIA are common in Africans; PVD may be less common than in Caucasians. There was no signifcant association of AMD grade with VMIA. | en_US |
dc.identifier.other | doi.org/10.1038/s41433-023-02737-z | |
dc.identifier.uri | http://ugspace.ug.edu.gh:8080/handle/123456789/40466 | |
dc.language.iso | en | en_US |
dc.publisher | Springer Nature | en_US |
dc.subject | vitreomacular interface abnormalities (VMIA) | en_US |
dc.subject | Ghanaian | en_US |
dc.subject | optical coherence tomography (SD-OCT) | en_US |
dc.title | Vitreomacular interface abnormalities in the Ghanaian African | en_US |
dc.type | Article | en_US |
Files
Original bundle
1 - 1 of 1
Loading...
- Name:
- Vitreomacular-interface-abnormalities-in-the-Ghanaian-AfricanEye-Basingstoke.pdf
- Size:
- 534.64 KB
- Format:
- Adobe Portable Document Format
- Description:
License bundle
1 - 1 of 1
No Thumbnail Available
- Name:
- license.txt
- Size:
- 1.71 KB
- Format:
- Item-specific license agreed upon to submission
- Description: