Report of the 1st African Enteric Viruses Genome Initiative data and Bioiniformatics workshop on whole genome analysis of some African rotavirus strains held in Bloemfontein, South Africa
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Date
2020-07-22
Journal Title
Journal ISSN
Volume Title
Publisher
Vaccine
Abstract
The University of the Free State - Next Generation Sequencing (NGS) Unit, Bloemfontein, South Africa,
hosted a data and bioinformatics workshop from 19 to 22 June 2018. The workshop was coordinated
by the African Enteric Viruses Genome Initiative (AEVGI) with support from the Bill & Melinda Gates
Foundation. The event introduced technologies in NGS and data analysis with focus on the rotavirus
(RV) genome. The workshop fostered interactions and networking between professionals, scientific
experts, technicians and students. The courses provided an overview of RV diarrhoea and its burden in
Africa, while highlighting the key resources and methodologies in NGS and advanced bioinformatics in
deciphering vaccine impact. It was concluded that, despite the reported significant decline in RV
associated-diarrhoea mortality and morbidity in Africa due to RV vaccine impact, the need for continuous
surveillance and genomic characterization to better understand the ever-changing dynamics of RV strains
is imperative.
Description
Research Article
Keywords
Rotavirus, Vaccine, Africa, Whole genome sequencing, Bioinformatics, Diarrhoea
Citation
M. M. Nyaga, S. Sabiu, V. N. Ndze et al., Report of the 1st African Enteric Viruses Genome Initiative data and Bioiniformatics workshop on whole genome analysis of some African rotavirus strains held in Bloemfontein, South Africa, Vaccine, https://doi.org/10.1016/j. vaccine.2020.06.010