Abstract:
The University of the Free State - Next Generation Sequencing (NGS) Unit, Bloemfontein, South Africa,
hosted a data and bioinformatics workshop from 19 to 22 June 2018. The workshop was coordinated
by the African Enteric Viruses Genome Initiative (AEVGI) with support from the Bill & Melinda Gates
Foundation. The event introduced technologies in NGS and data analysis with focus on the rotavirus
(RV) genome. The workshop fostered interactions and networking between professionals, scientific
experts, technicians and students. The courses provided an overview of RV diarrhoea and its burden in
Africa, while highlighting the key resources and methodologies in NGS and advanced bioinformatics in
deciphering vaccine impact. It was concluded that, despite the reported significant decline in RV
associated-diarrhoea mortality and morbidity in Africa due to RV vaccine impact, the need for continuous
surveillance and genomic characterization to better understand the ever-changing dynamics of RV strains
is imperative.