Trichomonas vaginalis infection in southern Ghana: clinical signs associated with the infection

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dc.contributor.authorAsmah, R.H.
dc.contributor.authorSquire, D.S.
dc.contributor.authorLymbery, A.J.
dc.contributor.authorWalters, J.
dc.contributor.authorAhmed, H.
dc.contributor.authorThompson, R.C.A.
dc.date.accessioned2019-12-13T08:53:36Z
dc.date.available2019-12-13T08:53:36Z
dc.date.issued2019-04-16
dc.descriptionResearch Articleen_US
dc.description.abstractTrichomonas vaginalis is the causative agent for the most prevalent non-viral sexually transmitted infection (STI) among women of child-bearing age. In Ghana, although the infection is prevalent, there is a dearth of data on the risk factors and symptoms associated with T. vaginalis infection. This study was conducted on 492 women visiting gynaecological and STI clinics in the Volta Region (VR) and Greater Accra Region (GAR) in southern Ghana. Wet mount microscopy and polymerase chain reaction (PCR) were used to diagnose T. vaginalis infection. Infection prevalence was 13.2% and 18.1% by WMM and PCR, respectively. Diagnosis by PCR was significantly more sensitive (McNemar’s test, p=0.0003). The regional prevalence of T. vaginalis infection by PCR was 21.7% in the VR and 12.8% in the GAR. There was a significant difference in prevalence between the two regions (Fisher’s exact test, p=0.02). T. vaginalis infection was associated with vaginal itch (odds ratio [OR]=1.71, p=0.04) and a history of engaging in oral sex (OR 1.90, p=0.04). A high prevalence of T. vaginalis infection was recorded among women visiting gynaecological and STI clinics in southern Ghana. There was no consistent association of infection with any recorded clinical signs and no clear risk factors for infection were identified.en_US
dc.description.sponsorshipMurdoch University International Postgraduate Studentship awarded by Murdoch Universityen_US
dc.identifier.otherdoi:10.1093/trstmh/trz019
dc.identifier.urihttp://ugspace.ug.edu.gh/handle/123456789/34168
dc.language.isoenen_US
dc.publisherRoyal Society of Tropical Medicine and Hygieneen_US
dc.relation.ispartofseries113;2019
dc.subjectruralen_US
dc.subjectsouthern Ghanaen_US
dc.subjectTrichomonas vaginalisen_US
dc.subjecturbanen_US
dc.subjectwomenen_US
dc.titleTrichomonas vaginalis infection in southern Ghana: clinical signs associated with the infectionen_US
dc.typeArticleen_US

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