Hepatitis B virus sero-prevalence amongst pregnant women in the Gambia

dc.contributor.authorBittaye, M.
dc.contributor.authorIdoko, P.
dc.contributor.authorEkele, B.A.
dc.contributor.authorObed, S.A.
dc.contributor.authorNyan, O.
dc.date.accessioned2019-05-20T10:14:27Z
dc.date.available2019-05-20T10:14:27Z
dc.date.issued2019-03
dc.description.abstractBACKGROUND: Infection with Hepatitis B virus (HBV) is a serious public health problem worldwide, with over 360 million carriers. Sixty million of these are resident in Sub-saharan Africa. Hepatitis B infection is the cause of Hepatocellular carcinoma (HCC), which is the second commonest cause of death from cancers among women in The Gambia. Vertical transmission is the commonest route of spread of Hepatitis B Virus in many endemic areas. The main aim of the study was to determine the sero-prevalence of Hepatitis B surface antigen (HBsAg) among pregnant women attending antenatal clinic at the Edward Francis Small Teaching Hospital, Banjul, The Gambia. METHODS: Four hundred and twenty six pregnant women were recruited from our antenatal clinics and tested for HBsAg. Serum Hepatitis B surface antigen (HBsAg) was tested using commercial rapid diagnostic Elisa kits at the point of care. RESULTS: A prevalence rate of 9.20% among all pregnant women studied was found. Women who were likely to have been vaccinated had a prevalence rate of 2.30% whiles those unlikely to have been vaccinated had a prevalence of 13.71%. There was a statistically significant difference between those likely to have been vaccinated and those unlikely to have been vaccinated. CONCLUSION: The prevalence of hepatitis B infection is very high among pregnant women at EFSTH as in the high endemic zone that is more than 8%. However the prevalence rate is lower than the national average of 15%. The prevalence is of moderate endemicity among the women who likely received vaccination during childhood. More interventions during pregnancy need to be undertaken if more successes are to be registered.en_US
dc.identifier.otherhttps://doi.org/10.1186/s12879-019-3883-9
dc.identifier.urihttp://ugspace.ug.edu.gh/handle/123456789/30105
dc.language.isoenen_US
dc.publisherBMC Infectious Diseasesen_US
dc.subjectPregnancyen_US
dc.subjectHepatitis B infectionen_US
dc.subjectSero-prevalenceen_US
dc.titleHepatitis B virus sero-prevalence amongst pregnant women in the Gambiaen_US
dc.typeArticleen_US

Files

Original bundle

Now showing 1 - 1 of 1
Loading...
Thumbnail Image
Name:
Hepatitis B virus sero-prevalence amongst pregnant women in the Gambia.pdf
Size:
399.35 KB
Format:
Adobe Portable Document Format
Description:

License bundle

Now showing 1 - 1 of 1
Loading...
Thumbnail Image
Name:
license.txt
Size:
1.6 KB
Format:
Item-specific license agreed upon to submission
Description: