T7 expression plasmids for producing a recombinant human G1P[8] rotavirus comprising RIX4414 sequences of the RV1 (Rotarix , GSK) vaccine strain

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dc.contributor.authorPhilip, A.A.
dc.contributor.authorAgbemabiese, C.A.
dc.contributor.authorPatton, J.T.
dc.contributor.authoret al.
dc.date.accessioned2023-12-20T11:32:37Z
dc.date.available2023-12-20T11:32:37Z
dc.date.issued2023
dc.descriptionResearch Articleen_US
dc.description.abstractThe live oral rotavirus RV1 (Rotarix) vaccine is formulated from the human G1P[8] RIX4414 virus. Based on RIX4414 sequences, T7 expression plasmids were constructed that supported recovery of recombinant RIX4414-like viruses by reverse genetics. These plasmids will advance the study of the RV1 vaccine, possibly allowing improvements to its efficacy.en_US
dc.identifier.other10.1128/MRA.00603-23
dc.identifier.urihttp://ugspace.ug.edu.gh:8080/handle/123456789/41078
dc.language.isoenen_US
dc.publisherMicrobiology Resource Announcementsen_US
dc.subjectreverse genetic analysisen_US
dc.subjectvaccinesen_US
dc.subjectrotavirusen_US
dc.titleT7 expression plasmids for producing a recombinant human G1P[8] rotavirus comprising RIX4414 sequences of the RV1 (Rotarix , GSK) vaccine strainen_US
dc.typeArticleen_US

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