Investigation of the Anti-Proliferative and Antioxidant Activities of Cocoa Kombucha

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dc.contributor.authorFrimpong, D.A.
dc.date.accessioned2018-02-15T12:51:31Z
dc.date.available2018-02-15T12:51:31Z
dc.date.issued2015-11
dc.descriptionMSc.en_US
dc.description.sponsorshipCocoa kombucha (CK) is a new alcoholic beverage developed from cocoa which has many health benefits, so its antioxidant activity and anti-proliferative activity in Jurkat P9 cancer cells were determined and compared to unfermented cocoa and selected standards. The antioxidant activity of CK extract was determined by DPPH assay and total phenolic content, as well as its iron reducing power. The MTT assay was used to determine the anti-proliferative activity of cocoa kombucha. Results indicated that cocoa kombucha had higher antioxidant activity, represented by significantly (p<0.05) higher reducing power and free radical scavenging activity, compared to the unfermented cocoa. However, both cocoa extracts did not show any anti-proliferative activity in Jurkat P9 leukemia cells compared to the standard anti-cancer drug, curcumin. These findings suggest that cocoa kombucha, at the concentrations used in this study, though showed significant antioxidant activity was not cytotoxic to the Jurkat P9 cells.en_US
dc.identifier.urihttp://ugspace.ug.edu.gh/handle/123456789/22744
dc.language.isoenen_US
dc.publisherUniversity Of Ghanaen_US
dc.subjectCocoaen_US
dc.subjectHealth Benefitsen_US
dc.subjectAntioxidant Activityen_US
dc.subjectGhanaen_US
dc.titleInvestigation of the Anti-Proliferative and Antioxidant Activities of Cocoa Kombuchaen_US
dc.typeThesisen_US

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