Laboratory Investigation of Suspected Cases of Chromosomal Abnormalities at the Korle-Bu Teaching Hospital.
dc.contributor.author | Tagoe, C.N.B. | |
dc.contributor.author | Sowah, E.T. | |
dc.contributor.author | Ayettey, A.S. | |
dc.contributor.author | Engmann, N.N.L. | |
dc.date.accessioned | 2019-11-05T11:00:34Z | |
dc.date.available | 2019-11-05T11:00:34Z | |
dc.date.issued | 1989-09 | |
dc.description | Journal Article on Chromosomal Abnormalities | en_US |
dc.description.abstract | Results of cytogenetic analysis carried out on 434 patients referred with clinical history suggestive of chromosomal abnormality showed a frequency of 27.4% (119/434) Of this number (119), 66.4% (79/119) had trisomy 21, made up of 71 regular Mongols [47,XX(Y), + 21] and 8 mosaics [46/47,XX(Y, +211. There was a male/female ratio of 3:2. Of the remaining 40, five were trisomy 13 and five trisomy 1& 26 of these had sex chromosome abnormality, out of which twenty were of the Turner's syndrome, three of intersex, two 0/ Klinefelter's syndrome, and one 47XYY. Among the 20 Turner syndrome patients fourteen were mosaic (46,XX/45,XO) and five homogeneous (45,XO) .. one patient had the 46,XY/45,XO pattern. Four structural chromosomal abnormalities were found. They consisted one each of 46,XX,D-,t(DqGq) +, 46,XXI46,XX,20q-(Philadelphia chromosome), 46,xx,q- and 46,XX/46,XX, types | en_US |
dc.identifier.uri | http://www.ghanamedj.org/archives/GMJ%201989%20Vol%2023%20No%203/Chromosomal%20abnormalities.pdf | |
dc.identifier.uri | http://ugspace.ug.edu.gh/handle/123456789/33340 | |
dc.language.iso | en | en_US |
dc.publisher | Ghana Medical Journal | en_US |
dc.relation.ispartofseries | 23;3 | |
dc.subject | Abnormal Chromosomes | en_US |
dc.subject | cytogenetic analysis | en_US |
dc.subject | Ghana | en_US |
dc.subject | Turner syndrome | en_US |
dc.title | Laboratory Investigation of Suspected Cases of Chromosomal Abnormalities at the Korle-Bu Teaching Hospital. | en_US |
dc.type | Article | en_US |
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