School of Biomedical and Allied Health Sciences
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Item Effect Of Self-Disclosure Of Stammering On Listeners’ Perceptions(University of Ghana, 2020-10) Tetteh, P.K.Background: Adults who stammer (AWS) experience discomfort when engaging in social interactions. Their stammering status negatively affect how their listeners perceive and engage with them. Listener perception therefore leads to several negative consequences like social anxiety and low self-esteem among persons who stammer (PWS). Self-disclosure is one of the leading therapies recommended for PWS to improve their listeners’ perception of them. However, evidence is inconclusive on its effectiveness, and empirical evidence in Ghana is non-existent. Aim: This study investigated how self-disclosure and gender affect listeners’ perceptions towards AWS. Method: A convenient sample of 210 undergraduate students listened to 4 videos from two speakers (1 male and 1 female) narrating a scene from a popular movie. The male and the female speaker each did or did not self-disclosed their stammering status. The listeners then rated their perceptions of the speakers’ personality, communication intent, communication competence and social competence. A 2-Way MANOVA was used to estimate main and interaction effects of self-disclosure and gender on listener perception. Results: Self-disclosure had positive effect on perceived communication intent, communication competence and social competence, but not personality. Female AWS were rated more favourably on communication competence and social competence than males. Male AWS were rated more positively on communication intent. There was significant interaction effect of gender and disclosure on listener perceptions. Female AWS who disclosed their status were rated more favourably than men who disclosed on perceived communication intent. Conclusion: The effectiveness of self-disclosure on listener perception depends on the perceived intent of the communication and gender of the AWS.Item Effect Of Cocoa On Ovarian Histology In Experimental Dipsomaniac Rabbits(University of Ghana, 2017-07) Kumaga, E.E.A.Background: Regular alcohol intake significantly increases reactive oxygen species (ROS) which magnify the levels of oxidative stress (OS) in the ovaries beyond physiological levels. Oxidative stress occurs due to an overabundance of ROS and the ineffectuality of scavengers. Alcohol is also known to perturb the feedback mechanisms of the hypothalamus-pituitary-gonadal (HPG) axis resulting in impairment of production and secretion of adequate quantity or potency of LH and FSH necessary for fertility. The usage of natural and synthetic antioxidants in treating and managing female infertility of OS etiology in patients is currently being investigated. Natural cocoa exhibits greater antioxidant capacity than many other flavanol-rich foods and food extracts. This suggests that cocoa as a nutraceutical may resolve OS related ovarian injury. Aim: This study investigated the ameliorative effect of natural cocoa on alcohol induced ovarian injury in rabbits. Methodology: Thirteen female rabbits of ages 5-7 months and weights 1.5-2.5 kg were put into 3 groups (Groups A, B and C) and given the following daily treatments for 7 weeks. Group A (n=5), Group B (n=5) and Group C (n=3). Group A, received cocoa from 6am to 6pm and 35% alcohol from 6pm to 6am ad libitum. Group B received water from 6am to 6pm and 35% alcohol ad libitum from 6pm to 6am. Group C received water for 24 hours. All rabbits had access to rabbit chow daily. Baseline serum levels of LH, FSH, GSH and SOD were measured and repeated at the end of the experiment (week 7). At termination, all rabbits were sacrificed and ovaries harvested. Volume density of follicles at different stages and stroma were estimated. Weight of rabbits and ovaries together with volume of ovaries were also determined. Results: Group B had low levels of serum LH and FSH (ANOVA, p<0.001) as compared with Groups C. Post treatment concentrations of GSH and SOD in Group A were not significantly different from that of Group C (ANOVA, p<0.05). Stereologic assessment of volume density of primordial follicles, corpora atretica and stroma showed significant differences between groups (ANOVA, p<0.05). Functional elements of the ovary parenchyma were preserved in Group A rabbits compared to Group B and C (ANOVA, p=0.05). Ovary weights and volumes did not vary significantly between the groups (ANOVA, p=0.75). Conclusion: Alcohol-induced structural and functional ovarian injury was significantly ameliorated in rabbits chronically fed alcohol but also given natural cocoa drink.Item Covid-19 In Patients Presenting With Malaria-Like Symptoms At Korle Bu Polyclinic, Accra(University Of Ghana, 2022-08) Asamoah, I.Malaria is one of Ghana's most frequent illnesses and the most common cause of febrile sickness. The prevalence of malaria in patients who visit the Korle Bu Polyclinic in Accra with malaria-like symptoms is around 8%. It is therefore essential to look into COVID-19's contribution to malaria-like symptoms. Most infectious diseases including COVID-19 and arboviral infections mimic malaria due to the overlapping of non-specific symptoms they both share. This study investigated COVID-19 in patients presenting with malaria-like symptoms at the Korle Bu Polyclinic, Accra. A cross-sectional study was conducted among patients presenting with malaria-like symptoms at the Korle Bu polyclinic from June to August, 2021. A total of 300 patients who qualify for Malaria Rapid Diagnostic Testing, and met the criteria for the study, were selected using simple random sampling. Two to three millilitres of whole blood, nasopharyngeal and oropharyngeal swab samples was collected for screening of Plasmodium falciparum and SARS-CoV-2 respectively. The whole blood sample was also used for COVID-19 antibody test and full blood count. Sixty out of three hundred (20%) study patients were positive for SARS-CoV-2 using Real-time PCR and twenty six out of three hundred (8.7%) tested positive using COVID-19 Rapid Antigen test. Majority were females (42/60; 70%), and participants had mean age of 28 years. Seven out of three hundred (2.3%) tested positive for Plasmodium falciparum using Malaria RDT and microscopy and eight out of three hundred (2.7%) using Nested Conventional PCR. Two coinfection of Plasmodium falciparum and SARS-CoV-2 were reported. Most of the patients came from the Ablekuma South district. Most patients with CT’s below 30 (High viral load) presented with 5 or more symptoms (p value <0.01). The most common symptom experienced by the study patients at the polyclinic was headache (95%; 57/60) followed by general body weakness and pain (78.3%;47/60), tiredness (60%; 36/60) and fever ( 51.7%; 31/60) Comorbidities reported were hypertension, diabetes, Asthma, hypertension and diabetes and none had sickle cell diseases. Most of the study patients had been previously exposure to SARS CoV-2 (113/300) and 66.7% (34/51) Astrazeneca vaccinated patients had no antibody. Due to the synergy of symptoms, screening for COVID-19 in patients presenting with malaria-like symptoms is vital for immediate diagnosis and treatment. Keywords: COVID-19, Korle Bu, AccraItem In-Vitro Evaluation Of Antibacterial Properties Of Euphorbia Hirta Against Selected Multidrug-Resistant Bacteria In Ghana.(University of Ghana, 2022-06) Gyabeng, J.Background: Treatment of infections is an important area of public health concern as the prevalence of multidrug-resistant (MDR) bacteria is on the rise. MDR bacteria are associated with high morbidity and mortality worldwide. Medicinal plants including Euphorbia hirta have shown effectiveness in the treatment of infections and have been one area of interest worldwide for the treatment of diseases due to their high antimicrobial properties against MDR bacteria. In Ghana, the continuous spread of MDR bacteria has resulted in prolonged illness, increased healthcare costs and heightened fatalities which can suddenly cripple the country’s economy. One way to reduce the burden of MDR bacteria is to screen for new classes of antimicrobials from natural products and medicinal plants. Thus, this research aimed to evaluate the antimicrobial properties of E. hirta against selected MDR bacteria in Ghana. Methodology: Five solvents systems (methanol, distilled water, ethyl acetate petroleum ether and dichloromethane) with varying polarities were used to extract E. hirta via cold and Soxhlet extraction methods. The agar-well diffusion method was used to determine the antimicrobial activity of the various extracts against some selected MDR bacteria. Column chromatographic technique was used to the separate most potent crude extract into fractions and their antimicrobial activity were determined. Fractions that showed antimicrobial activity were further purified using column chromatography. Purified fractions were analyzed for the functional groups of compounds present using gas chromatography mass spectrometer (GCMS). The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of crude ethyl acetate extracts and active fraction was determined. Results: Results from this study showed that, soxhlet maceration process had higher yield than cold maceration but the antimicrobial activity of extracts from both methods were the same. The University of Ghana http://ugspace.ug.edu.gh xvi Antimicrobial susceptibility test (AST) results revealed that K. pneumoniae isolates. recruited in the study were resistant to all extracts used. Furthermore, all test organisms were resistant to dichloromethane and petroleum ether extracts. Out of the 15 test organisms used, methanol and aqueous extracts were potent against 5 test organisms. Phytochemical analysis revealed the presence of phytoconstituents such as reducing sugars, phenolic compounds, saponins, flavonoids, anthracenosides and phytosterols. GC-MS analysis shows that 1,2,3-Benzenetriol is the probable sugars present in the active fraction. MIC and MBC results indicated that ethyl acetate extracts and the active fraction had the same MBC values with 3.13 mg/ml as their lowest MBC concentration. The MIC value recorded for crude ethyl acetate was between 50- 6.25 mg/ml whiles that of the active fraction (CF5) was between 50 -12.5 mg/ml. Conclusion; Polar extracts of whole E. hirta plant have antimicrobial activity with ethyl acetate extracts being the highest. The plant has the potential to be used as an antimicrobial agent. Therefore, in-vivo studies should be conducted using different polar solvents to extract the whole plant of E. hirta to exploit its antimicrobial activity in living thing.Item Bacterial Aetiology And Risk Factors Associated With Childhood Otitis Media In Accra, Ghana(University of Ghana, 2021-09) Bannah, V.Background: Otitis media (OM), also known as middle ear infection, has a high prevalence among young children. Young children have horizontally aligned Eustachian tubes (ET), smaller and shorter middle ear anatomical features and more frequent upper respiratory tract infections than adults. These make them more vulnerable to OM. The complications of OM include hearing loss, delayed speech development, impaired intellectual development, and societal challenges in later life. Nonetheless, there is a paucity of data regarding the bacterial aetiologies responsible for the condition and their associated antimicrobial susceptibility patterns, and little is known about the risk factors associated with OM. Aim: This study aimed to investigate the bacterial aetiologies and risk factors associated with otitis media among children in Accra, Ghana Materials and method: The research was a cross-sectional study in which children below 13 years old attending the ear, nose and throat clinics (ENT) of the Princess Marie Louise Children’s Hospital (PMLH), 37 Military Hospital and Mamprobi Hospital with suppurative otitis media were recruited during the study period. Following standard bacteriological methods, sterile ear swabs were used to take middle ear discharge from study participants for culture and antimicrobial susceptibility testing. A standard questionnaire was also used to collect data on socio-demographic characteristics, potential risk factors and clinical information. Results: Out of the 100 swabs from the 100 study subjects, 97 swabs gave positive yields, out of which 87.3% were pathogens. The most commonly-isolated pathogen was Pseudomonas aeruginosa (38.5%), followed by Klebsiella pneumoniae (19.8%) and Proteus mirabilis (11.5%). A high level of resistance was recorded for ampicillin, piperacillin-tazobactam, cefuroxime, amoxicillin-clavulanate, trimethoprim-sulfamethoxazole, tetracycline and ceftriaxone. Of the potential risk factors of ASOM and CSOM evaluated, only child history of ASOM showed a statistically significant association with the development of CSOM. Conclusion: Pseudomonas aeruginosa, Klebsiella pneumonia, and Proteus mirabilis were the common bacteria aetiologic agents of childhood OM. Poor responses to first-line antibiotics such as ampicillin and amoxicillin-clavulanate were reported, hence ciprofloxacin and gentamicin are recommended to be used in the management of OM in children. A history of ASOM was the risk factor identified to be associated with developing CSOM.Item Carriage Of Multi-Drug Resistant Enterobacterales And Acinetobacter Baumannii Among Hospitalised Paediatric Patients At The Child Health Department, Korle-Bu Teaching Hospital(University Of Ghana, 2022-08) Nelson, H.BACKGROUND: Infection and carriage of multidrug resistant (MDR) Enterobacterales and Acinetobacter baumannii are increasing globally and complicate the management of infections in children. Outbreaks of infections due to these MDR pathogens, particularly carbapenem-resistant Enterobacterales (CRE) and A. baumannii in hospitals are widespread and are a growing problem. Carriage of MDR pathogens is a precursor for invasive infections which are associated with high morbidity and mortality. This study determined the prevalence and epidemiology of MDR pathogens, with a focus on carbapenem-resistant Enterobacterales and A. baumannii among paediatric inpatients of the Korle-Bu Teaching Hospital. AIM: This study aimed at identifying the risk factors for carriage of carbapenem-resistant Enterobacterales and A. baumannii, and the molecular genotypes of carbapenemase-producing isolates, among paediatric inpatients at the Korle-Bu Teaching Hospital. METHOD: A cross-sectional study was conducted over 8 months period, from March to October 2021 at the Child Health Department, Korle-Bu Teaching Hospital. A systematic sampling method was used to recruit the participants. Relevant clinical data was extracted from participants’ medical records per a structured data collection instrument. Rectal swabs were collected from participants and inoculated onto MacConkey agar and incubated at 35-37°C for 18-24hrs. Different colonial morphotypes were identified by standard bacteriological techniques and confirmed with MALDI-TOF spectometry. Antimicrobial susceptibility testing was performed on all isolates. Carbapenem resistant isolates were screened for carbapenemase production using modified Hodge test. Multiplex polymerase chain reaction (PCR) and gel imaging techniques were used to evaluate the presence, and to characterise carbapenemase genes present. Frequency tables were used to University of Ghana http://ugspace.ug.edu.gh v summarize the prevalence and distribution of MDR organisms. Associations between risk factors and carriage of carbapenem resistant organisms were analysed using multinomial logistic regression. RESULTS: A total of 344 bacteria isolates; 331 Enterobacterales and 13 A. baumannii were isolated from rectal swabs of 299 paediatric inpatients ≤ 13years. The most common isolates were E. coli (60.5%, n = 208), K. pneumoniae (29.9%, n = 103) and A. baumannii (3.8%, n = 13). Prevalence of MDR among the isolated organisms were 75.6% (n = 260); E. coli (74.0%, n = 154), K. pneumoniae (76.7%, n = 79), and A. baumannii (100%, n = 13). Carriage of ESBL producing Enterobacterales was 72.6% (n = 217); with E. coli (46.8%, n = 140) and K. pneumoniae (25.1%, n = 75) being the most predominant ESBL phenotypes. Faecal carriage of carbapenem resistant bacteria was 23.1% (n = 69). E. coli (11%, n = 33), K. pneumoniae (7.4%, n = 22), A. baumannii (3.3%, n = 10) were the most common carbapenem resistant isolates. 52.2% (n = 36) of these carbapenem resistant isolates expressed phenotypic carbapenemase activity by the modified Hodge test (MHT). Thirty two (46.4%) were found to harbour at least one carbapenemase gene; blaOxa-48 (20.3%, n = 14), blaVIM (15.9%, n = 11), blaNDM (4.4%, n = 3), and blaIMP (5.8%, n = 4). Five (15.6%) harboured 2 carbapenemase genes, but none harboured 3 or more genes. Prior exposure to carbapenems and fluoroquinolones increased the odds of carriage of carbapenem-resistant Enterobacterales and A. baumannii by approximately two folds. CONCLUSION: This study reports high faecal carriage of MDR bacteria among paediatric inpatients of the Korle-Bu Teaching Hospital. This includes carbapenem-resistant Enterobacterales and A. baumannii with blaOxa-48 and blaVIM carbapenemase genes being the commonest. Prior antibiotic exposure to carbapenems and fluoroquinolones within the past year were significant risk factors for carriage of carbapenem-resistant isolates.Item Characterization Of Uropathogenic Escherichia Coli (Upec) In Hiv Seropositive Women With Asymptomatic Bacteriuria(University Of Ghana, 2022-08) Amegbletor, H.K.BACKGROUND: Asymptomatic bacteriuria (ASB), a precursor for Urinary tract infection (UTI), is high among People living with HIV (PLHIV). E. coli is the most implicated organism. An understanding of the risk factors for ASB, virulence genes and resistance profile of uropathogens among this population is important to the management and control. AIM: To characterize uropathogenic E. coli (UPEC) in HIV seropositive women with asymptomatic bacteriuria METHODOLOGY: This cross-sectional study was carried out at St. Martin de Pores Hospital, Eikwe in the Western Region of Ghana. A structured questionnaire was used to extract clinical information from the folders of 400 HIV seropositive women. The information included patient demographics, history of hospitalization, HAART treatment initiation date and WHO disease stage. Urine samples were obtained, cultured and identified with MALDI TOF biotyper. Antibiotic resistance pattern was determined, and genes coding for virulence and integrons were screened for using Multiplex PCR and gel imaging techniques. RESULTS: From the 400 samples cultured, 21.15% (85/400) were positive. The most prevalent organisms were; Escherichia coli 69.4% (59/85), Enterococcus faecalis 8.2% (7/85), Klebsiella pneumoniae 7.0% (6/85)), Proteus mirabilis 7.0% (6/85), Staphylococcus hemolyticus 3.5% (3/85). All uropathogenic E. coli isolates were resistant to ampicillin and 98.3% (58/59), resistant to trimethoprim sulfamethoxazole, followed by tetracycline 94.9% (56/59), cefuroxime 74.6% (45/59), amoxiclav 49.2% (30/59) and ciprofloxacin 32.2% (19/59). The lowest resistance was recorded to meropenem and fosfomycin at 1.7% and nitrofurantoin 6.8% (4/59). The commonest virulence genes observed were ChuA 66.1% (n=39/59), PapC 57.6% (n=34/59), cnf1 50.8% (n=30/59), kpsMTII 45.8% (n=27/59), iuAt 35.6% (n=21/59) and usp gene 8.5% (n=5/59). Two isolates (3.4%) harbored all 5 genes (iuAt, cnf1, papC, chuA, kpsMTII). Five isolates haboured iuAt, cnf1, papC and chuA (8.5%, n=5/59). Three genes (iuAt, cnf1, papC) were all observed in 6 isolates (10.2%, n=6/59) whilst 7 isolates (12%, n=7/59) were found to harbor genes iuAt and cnf1. The commonest integron was intI 42% (n=25/59) followed by intII 20% (n=12/59). Viral load [(OR=1.000, 95% CI, 1.000-1.000) (p = 0.295)], HAART duration [(OR=1.036, 95% CI, 0.287-1.042) (p=0.287)], age [(OR=1.020, 95% CI, 0.999-1.042) (p = 0.06)] and WHO disease stage [(OR=1.286, 95% CI, 0.535-1.6) (p = 0.885)] showed no significant association with the occurrence of asymptomatic bacteriuria (p≥0.05). HAART duration was observed to be a predictor of resistance to amoxiclav [(OR=1.329, 95% CI, 1.113-1.588) (p= 0.002)]. CONCLUSION: This study showed that asymptomatic bacteriuria is common among women living with HIV (WLHIV) visiting Eikwe district hospital, with no association with age, viral load, WHO disease stage and HAART duration. High prevalence of multidrug resistant UPEC coupled with the high carriage of virulence genes indicates that WLHIV are at a high risk of developing urinary tract infections with the potential for complications. There is a need for regular monitoring of bacteriuria and antibiotic susceptibility testing among this population.Item Maternal Serum Angiopoietin And Vascular Endothelial Growth Factor (Vegf) Levels In Preeclampsia And Pregnancy Outcomes(University Of Ghana, 2021-09) Bayor, F.Introduction: Preeclampsia remains a major obstetric complication globally, accompanied by a significant burden of adverse maternal and perinatal outcomes especially among Sub-Saharan African (SSA) countries including Ghana. The high maternal and perinatal outcomes of preeclampsia may be due to the lack of consensus on the ideal clinical and therapeutic intervention which stems from the insufficient knowledge on the actual etiology and pathophysiological mechanisms that underline the disease progression. Aim: To explore maternal serum levels of angiopoietins (1 and 2), Vascular endothelial growth factor (VEGF), and pregnancy outcomes in preeclampsia. Methods: The study was a comparative cross-sectional study with cases and controls, conducted at the Obstetrics and Gynaecology Department of the Korle-Bu Teaching Hospital (KBTH). A systematic random sampling technique was used to recruit study participants consisting of women diagnosed with preeclampsia (cases), pregnant normotensives (control group 1), and non-pregnant normotensives (control group 2). A structured data extraction form was used to collect data on the demographic and clinical features of the study participants. Results: A total of 263 women including 75 non-pregnant normotensives, 94 pregnant normotensives, and 94 with established diagnosis of preeclampsia (PE) were enrolled. The study revealed that maternal serum VEGF [4.71 (IQR: 3.65, 7.93) pg/ml], Ang-2 levels [1.25 (IQR: 0.90, 2.15) ng/ml] and VEGF/Ang-2 ratio [3.85 (IQR: 1.91, 11.38)] in the PE group were significantly lower than in the normotensives controls. Although elevated maternal serum Ang-1 levels were found, the difference between women with PE and normotensive controls did not reach statistical significance (p>0.05). VEGF levels were significantly lower in early-onset PE [(3.89 (2.87, 4.78)pg/ml;p=0.014] than in late-onset PE [5.23 (3.78, 16.97) pg/ml] while Ang-1/VEGF ratio was found to be higher in early-onset PE [20.62(15.76,Item Phenotypic And Genotypic Detection Of Carbapenemase-Producing Escherichia Coli And Klebsiella Pneumoniae In Accra, Ghana(University Of Ghana, 2021-07) Dwomoh, F.P.Background: Escherichia coli and Klebsiella pneumoniae belong to the Enterobacteriaceae family, and are pathogens of high clinical significance. They are prone to acquiring antibiotic resistance genes, including those encoding carbapenemases, which confer resistance to carbapenems (the current drugs of last resort against infections with multidrug-resistant [MDR] Enterobacteriaceae). However, little is known about carbapenemase-producing E. coli and K. pneumoniae in Ghana. Aim: To investigate the occurrence of carbapenem resistance among MDR E. coli and K. pneumoniae isolated from clinical specimens in Accra using phenotypic and genotypic methods. Methodology: The study was cross-sectional, involving 144 clinical MDR E. coli and K. pneumoniae isolates originating from 15 different sample types from the Central Microbiology Laboratory of the Korle Bu Teaching Hospital between the periods of December 2020 to March 2021. The isolates were re-cultured, subsequently identified using standard biochemical tests, and subjected to antibiotic susceptibility testing using the Kirby-Bauer method. Carbapenem resistance was determined based on imipenem, meropenem, and ertapenem zones of inhibition, as well as minimum inhibitory concentrations (MICs); carbapenemase production was confirmed phenotypically with the Modified Hodge test (MHT) and Modified Carbapenem Inactivation Method (mCIM) and genotypically with multiplex PCR targeting blaKPC, blaIMP, blaNDM, blaVIM, and blaOXA-48. Results: Of the 144 MDR isolates, 69.4% were E. coli, and 30.6% were K. pneumoniae. The distribution of antimicrobial resistance rates among them were ampicillin (97.2%), cefuroxime (93.1%), sulfamethoxazole-trimethoprim (86.8%), tetracycline (85.4%), cefotaxime and cefpodoxime (77.1% each), amoxicillin-clavulanate (75%), ceftriaxone (73.6%), ciprofloxacin (70.8%), levofloxacin (66.0%), cefepime (65.3%), ceftazidime (64.6%), gentamicin (48.6), piperacillin-tazobactam (40.3%), cefoxitin (14.6%), amikacin (13.9%), ertapenem and meropenem (5.6% each), and imipenem (2.8%). In total, 5.6% (8/144) of them were carbapenem-resistant (carbapenem MIC range = 0.094–32.0 μg/ml), with 75% (6/8) of these testing positive by the phenotypic tests and 62.5% (5/8) by the genotypic test (of which 80% [4/5] carried blaOXA-48 and 20% (1/5) blaNDM). The blaVIM, blaIMP, and blaKPC genes were not detected. Conclusion: Although the rates of antibiotic resistance among the isolates were high, the prevalence of carbapenemase producers were low. There is evidence that blaOXA-48 and blaNDM may be circulating in Ghana, warranting upscaling of antimicrobial resistance surveillance programmes and fortification of infection prevention and control programmes in the country.Item Dietary Habits And Physical Inactivity Of Adolescents During Covid-19 Period(University Of Ghana, 2021-12) Mensah, F.K.Background: It is known that physical inactivity is highly prevalent and dietary habits are poor among adolescents. These are the major risk factors for obesity in adolescents. During the COVID-19 pandemic, physical inactivity habits has been shown to be influenced due to restriction in movement and dietary habits have also been affected due to stress accompanying the pandemic. Aim: The aim of this study was to determine the association between poor dietary habits and physical inactivity of adolescents during the COVID-19 period. Methodology: A cross-sectional study design was employed for this research. Balloting and systematic sampling techniques were used to recruit adolescents between 15-19 years from Wesley Grammar School and Ideal College. Data collection was carried out from June to August 2021 (after the COVID-19 lockdown period). The Three- Factor Eating Questionnaire and Food Frequency Questionnaire were used to collect information on dietary habits and the International Physical Activity Questionnaire assessed physical activity information. IBM Statistical Package for Social Sciences (SPSS) version 20 was used for analysis. Continuous variables such as age were analysed using descriptive statistics summarised into means and standards deviation. Categorical variables such as dietary habits and physical activity levels were summarized into frequencies and percentages. Pearson chi-square test was employed to determine associations between dietary habits and physical inactivity. Results: Skipping meals, snacking and immoderate fat intake (eating fried and oily foods often) showed higher prevalence of 69.3%, 67.1% and 56.1% respectively. Majority (89.2%) of the participants had low physical activity level. There was significant association between time spent watching TV and intake of unpolished cereals (p= 0.018), fast foods (p= 0.001) and pastries (p = 0.050). There was no significant association between time spent on the computer and the various food groups, except for intake of unpolished cereals (p=0.003) and fast foods (p=0.013). In addition, significant association was found for time spent reading and frequency of consumption of legumes (p= 0.010) and pastries consumption (p ≤ 0.001). Conclusion: Dietary habits were generally unhealthy (poor) and physical inactivity was high among the participants during COVID-19 period. Some associations were found between sedentary behaviours and poor dietary habits.