Browsing by Author "Djankpa, F.T."
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Item Assessing the vibration perception threshold in a community sample of adult Ghanaians(PLOS ONE, 2023) Djankpa, F.T.; Amoah, A.G.B.; Adzaku, F.K.; Aidoo, E.; BoatengI, I.Background The vibration perception threshold (VPT) helps evaluate human somatosensory function and diagnose peripheral neuropathy. To optimize its use as a primary neurologic tool, it is imperative to establish its typical values in healthy subjects and assess the factors affecting its variability in an individual to ensure consistency in its application. Methods Demographic data and a brief medical history were collected from 391 non-diabetic adults aged 30–80 at Kpone-on-Sea in Ghana. The VPT was measured at the tip of the big toe, the medial malleolus, the tip of the middle finger, and the head of the ulna of each participant using a Horwell Neurothesiometer. The variability of VPT was assessed vis-à-vis the follow ing factors: gender, age, fasting plasma sugar and body mass index. Results The mean age of participants was 48.4 ± 0.7 years, and the female-to-male ratio was 1.46. The overall VPT values ranged from 5.74 ± 0.14 volts to 8.55 ± 0.18 volts in the lower limbs and 3.61 ± 0.06 volts to 5.00 ± 0.08 volts in the upper limbs. Age was found to be the only factor that could predict VPT for both the lower and upper limbs (P < 0.001). One-Way Anal ysis of Variance with Tukey’s posthoc showed that the VPT in the feet was significantly higher than that in the hands. Conclusions Generally, the VPT was high on proximal sites and low on distal sites indicating that the vibration sensation increased from proximal to distal direction. Therefore, distal areas should be used for VPT testing with a Neurothesiomer. Age was found to be the only factor that affected VPT variability. Hence, the practical application of VPT will require age-specific reference ranges to cater for older adults.Item Determination of the vibration perception threshold (VPT) in adult non-diabetic Ghanaians using a Neurothesiometer(2012) Djankpa, F.T.; Adzaku, F.K.; Osunuga, A.; Amoah, A.G.B.; Antwi, D.A.; Osunuga, O. A.; Amoah, S.K.Item Development of a Bait System for the Pharaoh’s Ant, Monomorium Pharaonis L. (Hymenoptera: Formicidae)(2011) Osae, M.Y.; Cobblah, M.A.; Djankpa, F.T.; Lodoh, E.; Botwe, P.K.Item Prolonged ingestion of dietary cocoa attenuates hemoglobin glycation associated with diabetes mellitus in rats.(IDOSI Publications, 2012) Amoah, S.K.; Osonuga, A.; Djankpa, F.T.; Osonuga, O.A.; Addai, F.K.; Affram, K.O.; Dennis, E.E.; Ayettey, A.S.Cocoa contains numerous polyphenols with laudable antioxidant activity. Glycation has been implicated in the pathogenesis of complications of diabetes mellitus. We investigate the effect of coca on hemoglobin glycation in rats experimentally induced with diabetes. 21 female Sprague-Dawley rats aged 21 weeks were randomly divided into control "C" and diabetic - diabetics fed cocoa "DC" and diabetics not fed cocoa "D" - groups of 6, 8 and 7 rats respectively. All rats were fed rat chow; C and D groups were fed tap water while the DC group were fed 2% w/v natural cocoa powder in tap water ad libitum. Diabetes was induced by a single intravenous shot of streptozotocin (53 mg/kg body weight). Ten weeks post-diabetes, 1ml of blood aspirated from the left ventricle and stored in a plastic tube containing ethylene diamine tetraacetic acid and used to determine the glycated haemoglobin (HbA1c) concentration of each rat using a DCA 2000 plasma 1c analyzer. Data was analyzed using ANOVA and posthoc Bonferroni's Multiple Comparison Test of GraphPad Prism (3.0). Percentage hemoglobin glycation significantly reduced (p < 0.0001) reduced from 12.8±0.50 to 7.8±0.27 in D and DC groups respectively but did not attain levels observed in the controls (3.90±0.10). Cocoa powder and other cocoa products can be administered alongside current diabetes management protocols to improve patients' outcome.