Browsing by Author "Ameade, E.P.K."
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Item Co-Occurrence of G6PD Deficiency and SCT among Pregnant Women Exposed to Infectious Diseases(Journal of Clinical Medicine, 2023) Helegbe, C.K.; Wemakor, A.; Ameade, E.P.K.; Anabire, N.G.; Anaba, F.; Bautista, J.M.; Zorn, B.G.During pregnancy, women have an increased relative risk of exposure to infectious diseases. This study was designed to assess the prevalence of the co-occurrence of glucose-6-phosphate dehydrogenase deficiency (G6PDd) and sickle cell trait (SCT) and the impact on anemia outcomes among pregnant women exposed to frequent infectious diseases. Over a six-year period (March 2013 to October 2019), 8473 pregnant women attending antenatal clinics (ANCs) at major referral hospitals in Northern Ghana were recruited and diagnosed for common infectious diseases (malaria, syphilis, hepatitis B, and HIV), G6PDd, and SCT. The prevalence of all the infections and anemia did not differ between women with and without G6PDd (χ 2 < 3.6, p > 0.05 for all comparisons). Regression analysis revealed a significantly higher proportion of SCT in pregnant women with G6PDd than those without G6PDd (AOR = 1.58; p < 0.011). The interaction between malaria and SCT was observed to be associated with anemia outcomes among the G6PDd women (F-statistic = 10.9, p < 0.001). Our findings show that anemia is a common condition among G6PDd women attending ANCs in northern Ghana, and its outcome is impacted by malaria and SCT. This warrants further studies to understand the impact of antimalarial treatment and the blood transfusion outcomes in G6PDd/SCT pregnant women.Item Co-Occurrence of G6PD Deficiency and SCT among Pregnant Women Exposed to Infectious Diseases(Journal of Clinical Medicine, 2023) Helegbe, G.K.; Wemakor, A.; Ameade, E.P.K.; et albstract: During pregnancy, women have an increased relative risk of exposure to infectious diseases. This study was designed to assess the prevalence of the co-occurrence of glucose-6-phosphate dehydrogenase deficiency (G6PDd) and sickle cell trait (SCT) and the impact on anemia outcomes among pregnant women exposed to frequent infectious diseases. Over a six-year period (March 2013 to October 2019), 8473 pregnant women attending antenatal clinics (ANCs) at major referral hospitals in Northern Ghana were recruited and diagnosed for common infectious diseases (malaria, syphilis, hepatitis B, and HIV), G6PDd, and SCT. The prevalence of all the infections and anemia did not differ between women with and without G6PDd (χ 2 < 3.6, p > 0.05 for all comparisons). Regression analysis revealed a significantly higher proportion of SCT in pregnant women with G6PDd than those without G6PDd (AOR = 1.58; p < 0.011). The interaction between malaria and SCT was observed to be associated with anemia outcomes among the G6PDd women (F-statistic = 10.9, p < 0.001). Our findings show that anemia is a common condition among G6PDd women attending ANCs in northern Ghana, and its outcome is impacted by malaria and SCT. This warrants further studies to understand the impact of antimalarial treatment and the blood transfusion outcomes in G6PDd/SCT pregnant women.Item Epidemiology, ecology and human perceptions of snakebites in a savanna community of northern Ghana(PLoS Neglected Tropical Diseases, 2019-06-25) Musah, Y.; Ameade, E.P.K.; Attuquayefio, D.K.; Holbech, L.H.Worldwide, snakebite envenomations total ~2.7 million reported cases annually with ~100,000 fatalities. Since 2009, snakebite envenomation has intermittently been classified as a very important ‘neglected tropical disease’ by the World Health Organisation. Despite this emerging awareness, limited efforts have been geared towards addressing the serious public health implications of snakebites, particularly in sub-Saharan Africa, where baseline epidemiological and ecological data remain incomplete. Due to poverty as well as limited infrastructure and public health facilities, people in rural Africa, including Ghana, often have no other choice than to seek treatment from traditional medical practitioners (TMPs). The African ‘snakebite crisis’ is highlighted here using regionally representative complementary data from a community-based epidemiological and ecological study in the savanna zone of northern Ghana. Methodology and findings Our baseline study involved two data collection methods in the Savelugu-Nanton District (in 2019 the district was separated into Savelugu and Nanton districts) in northern Ghana, comprising a cross-sectional study of 1,000 residents and 24 TMPs between December 2008 and May 2009. Semi-structured interviews, as well as collection of retrospective snakebite and concurrent rainfall records from the Savelugu-Nanton District Hospital and Ghana Meteorological Authority respectively over 10-years (1999–2008) were used in the study. Variables tested included demography, human activity patterns, seasonality, snake ecology and clinical reports. Complementary data showed higher snakebite prevalence during the rainy season, and a hump-shaped correlation between rainfall intensity and snakebite incidences. Almost 6% of respondents had experienced a personal snakebite, whereas ~60% of respondents had witnessed a total of 799 snakebite cases. Out of a total of 857 reported snakebite cases, 24 (~2.8%) died. The highest snakebite prevalence was recorded for males in the age group 15–44 years during farming activities, with most bites occurring in the leg/foot region. The highest snakebite rate was within farmlands, most severe bites frequently caused by the Carpet viper (Echis ocellatus). Conclusion The relatively high community-based prevalence of ~6%, and case fatality ratio of ~3%, indicate that snakebites represent an important public health risk in northern Ghana. Based on the high number of respondents and long recording period, we believe these data truly reflect the general situation in the rural northern savanna zone of Ghana and West Africa at large. We recommend increased efforts from both local and international health authorities to address the current snakebite health crisis generally compromising livelihoods and productivity of rural farming communities in West Africa.Item Green Care as Alternative Therapy: The Situation in Ghana(Hindawi, 2021) Ameade, E.P.K.; Amoah, L.A.O.; Ofori, B.Y.Green care, an alternative healthcare system that involves the use of nature, is proven to be useful in the management of organic and psychological disorders worldwide. There are various forms of Green care including Animal-Assisted Therapy (AAT), a type where animals play pivotal roles in the healing process and is widely used in many developed countries. We assessed the level of awareness and attitude towards Green care among medical students of Ghana. Using a cross-sectional study design and a semistructured questionnaire designed on Google Forms, data were collected from randomly selected 4th-, 5th-, and 6th-year medical students of the University for Development Studies, Tamale, Ghana. )e data submitted by 206 of the students were analyzed using Statistical Package for the Social Sciences, Version 25, and the results were presented as frequencies, percentages, and charts. )e association between sociodemographic characteristics of respondents and awareness about Animal-Assisted )erapy (AAT) was considered significant at p < 0.05. )e study found that only 7 (3.4%) of the medical students had ever heard of Green care while a higher number of 36 (17.5%) were aware of AATmostly through movies and television. However, the majority, 122 (59.3%), had a positive attitude towards the introduction of AAT, into their medical training curriculum. Up to 146 (70.9%) of the respondents suggested lectures and practical sessions as their preferred way of acquiring knowledge and skills on AAT. Only the sex of the respondents was significantly associated with awareness of AAT, with females having a better awareness of AAT (28.6% vs. 11.0%, p = 0.003). We conclude that awareness of Green care practices among medical students in Ghana was highly inadequate, but the desire of the majority of them to acquire knowledge and skills in this proven alternative therapy makes its future use in Ghana promising.