Managing Vibrio cholerae with a local beverage: preparation of an affordable ethanol based hand sanitizer

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dc.contributor.authorAdi-Dako, O.
dc.contributor.authorOsei-Asare, C.
dc.contributor.authorOppong, E.E.
dc.contributor.authorApenteng, J.A.
dc.contributor.authorKumadoh, D.
dc.contributor.authorAnsah, A.A.
dc.contributor.authorOhemeng, A.
dc.date.accessioned2020-01-23T09:51:18Z
dc.date.available2020-01-23T09:51:18Z
dc.date.issued2020-01-10
dc.descriptionResearch Articleen_US
dc.description.abstractResearch indicates an increased use of hand sanitizers globally, and in particular developing countries where bacterial epidemics such as cholera are common. While there is evidence of availability, high demand and use of hand sanitizers, the incidence of cholera in developing countries remains unabated. Several reasons have been put forward, and cost of hand sanitizers remains dominant. It is in response to this contradictory situation of availability but limited access, that this study was conducted to present an alternative option of formulating a high quality and cost effective ethanol-based sanitizer from a Ghanaian local beverage (akpeteshie). The concentration of ethanol in akpeteshie was determined using gas chromatography. An Ethanol based hand sanitizer (Sample C) was formulated with akpeteshie and tested against Vibrio cholerae using the microbial time -kill kinetics assay. Commercially available ethanol based Equi-Clean hand sanitizer (62%) (Sample D) was used as the standard. Results show that the akpeteshie contained 73.08% ethanol and formulated product (Sample C) contained 63.70% ethanol. Viscosity and pH of Sample C were; 89 rpm (1.48 cps) and 7.30 respectively whiles that of Sample D were; 80 rpm (1.33 cps) and 7.50 respectively. The formulated product (Sample C) was effective against Vibrio cholerae with a gradual reduction in microbial count upon exposure to the organisms at time intervals of 0, 5, 15, 30, 60 and 120 min.en_US
dc.identifier.otherhttps://doi.org/10.1016/j.heliyon.2019.e03105
dc.identifier.urihttp://ugspace.ug.edu.gh/handle/123456789/34617
dc.language.isoenen_US
dc.publisherHeliyonen_US
dc.relation.ispartofseries6;2020
dc.subjectAnalytical chemistryen_US
dc.subjectNatural product chemistryen_US
dc.subjectPharmaceutical chemistryen_US
dc.subjectPublic healthen_US
dc.subjectAkpeteshieen_US
dc.subjectGhanaen_US
dc.subjectTime-kill testen_US
dc.subjectVibrio choleraeen_US
dc.subjectEthanol based hand sanitiser (EBHS)en_US
dc.subjectLocal ginen_US
dc.subjectGas chromatographyen_US
dc.subjectNatural producten_US
dc.titleManaging Vibrio cholerae with a local beverage: preparation of an affordable ethanol based hand sanitizeren_US
dc.typeArticleen_US

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