First molecular identifcation of multiple tick-borne pathogens in livestock within Kassena-Nankana, Ghana

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dc.contributor.authorAddo, S.O.
dc.contributor.authorBentil, R.E.
dc.contributor.authorYartey, K.N.
dc.contributor.authorAnsah‑Owusu, J.
dc.contributor.authorBehene, E.
dc.contributor.authorOpoku‑Agyeman, P.
dc.contributor.authorBruku, S.
dc.contributor.authorWilson, M.D.
dc.contributor.authorDadzie, S.K.
dc.contributor.authoret al.
dc.date.accessioned2023-02-09T20:42:47Z
dc.date.available2023-02-09T20:42:47Z
dc.date.issued2023
dc.descriptionResearch Articleen_US
dc.description.abstractThe risk of pathogen transmission continues to increase significantly in the presence of tick vectors due to the trade of livestock across countries. In Ghana, there is a lack of data on the incidence of tick-borne pathogens that are of zoonotic and veterinary importance. This study, therefore, aimed to determine the prevalence of such pathogens in livestock using molecular approaches. A total of 276 dry blood spots were collected from cattle (100), sheep (95) and goats (81) in the Kassena-Nankana Districts. The samples were analyzed using Polymerase Chain Reaction (qPCR) and conventional assays and Sanger sequencing that targeted pathogens including Rickettsia, Coxiella, Babesia, Theileria, Ehrlichia and Anaplasma. An overall prevalence of 36.96% was recorded from the livestock DBS, with mixed infections seen in 7.97% samples. Furthermore, the prevalence of infections in livestock was recorded to be 19.21% in sheep, 14.13% in cattle, and 3.62% in goats. The pathogens identified were Rickettsia spp. (3.26%), Babesia sp. Lintan (8.70%), Theileria orientalis (2.17%), Theileria parva (0.36%), Anaplasma capra (18.48%), Anaplasma phagocytophilum (1.81%), Anaplasma marginale (3.26%) and Anaplasma ovis (7.25%). This study reports the first molecular identification of the above-mentioned pathogens in livestock in Ghana and highlights the use of dry blood spots in resource-limited settings. In addition, this research provides an update on tick-borne pathogens in Ghana, suggesting risks to livestock production and human health. Further studies will be essential to establish the distribution and epidemiology of these pathogens in Ghana.en_US
dc.identifier.otherhttps://doi.org/10.1186/s44149-022-00064-6
dc.identifier.urihttp://ugspace.ug.edu.gh:8080/handle/123456789/38612
dc.language.isoenen_US
dc.publisherAnimal Diseasesen_US
dc.subjectLivestocken_US
dc.subjectRickettsiaen_US
dc.subjectBabesiaen_US
dc.subjectTheileriaen_US
dc.subjectEhrlichiaen_US
dc.subjectAnaplasmaen_US
dc.titleFirst molecular identifcation of multiple tick-borne pathogens in livestock within Kassena-Nankana, Ghanaen_US
dc.typeArticleen_US

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