Identification of a new variable number tandem repeat locus in Mycobacterium ulcerans for potential strain discrimination among African isolates

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dc.contributor.authorAblordey, A.
dc.contributor.authorFonteyne, P.-A.
dc.contributor.authorStragier, P.
dc.contributor.authorVandamme, P.
dc.contributor.authorPortaels, F.
dc.date.accessioned2019-02-19T11:05:50Z
dc.date.available2019-02-19T11:05:50Z
dc.date.issued2007-07
dc.description.abstractIntra-species discrimination in the highly clonal pathogen Mycobacterium ulcerans was studied in a diverse collection of isolates by PCR amplification of a short sequence repeat locus containing heterogeneous arrays of tri-nucleotide repeats with an ACC consensus pattern. Post-amplification analysis indicated excellent typeability and identified five M. ulcerans alleles, including a unique Angolan type differentiated for the first time among a genetically conserved cluster of African isolates. These results are consistent with previously investigated independent markers, and provide an additional locus for variable number tandem repeat-based typing of M. ulcerans. © 2007 The Authors; Journal compilation © 2007 Blackwell Publishing Ltd.en_US
dc.identifier.otherVolume 13, Issue 7,Pages 734-736
dc.identifier.otherhttps://doi.org/10.1111/j.1469-0691.2007.01716.x
dc.identifier.urihttp://ugspace.ug.edu.gh/handle/123456789/27623
dc.language.isoenen_US
dc.publisherClinical Microbiology and Infectionen_US
dc.subjectDiscriminationen_US
dc.subjectMycobacterium ulceransen_US
dc.subjectPCRen_US
dc.subjectTypingen_US
dc.subjectVariable number tandem repeaten_US
dc.titleIdentification of a new variable number tandem repeat locus in Mycobacterium ulcerans for potential strain discrimination among African isolatesen_US
dc.typeArticleen_US

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