High Levels of Knockdown Resistance in Anopheles coluzzii and Anopheles gambiae (Diptera: Culicidae), Major Malaria Vectors in Togo, West Africa: A 2011 Monitoring Report
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Date
2013-03-29
Journal Title
Journal ISSN
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Publisher
Journal of Medical Entomology
Abstract
A survey of susceptibility to DDT, deltamethrin, bendiocarb, and chlorpyrifos-methyl was conducted in five
localities in 2011 in Togo, West Africa, to assess the insecticide resistance status of Anopheles gambiae s.l.
(Diptera: Culicidae). Female populations of An. gambaie s.l. emerged from collected larvae (F0) were exposed to
insecticide-impregnated papers using World Health Organization test kits for adult mosquitoes; the susceptible
reference strain Kisumu was used as a control. Resistance to DDT and deltamethrin was observed within the
mosquito populations tested. Anopheles gambiae s.s. and Anopheles coluzzii represented the only species recorded
in the study sites. The frequency of knockdown resistance (kdr L1014F) mutation determined using polymerase
chain reaction diagnostic tests was lower in An. gambiae than in An. coluzzii in all of the localities except
Kolokopé. Further investigations of An. gambiae s.l. resistance are needed in Togo to help the National Malaria
Control Programme in vector control decision making and implementation of resistance management strategy.
Description
Research Article
Keywords
Anopheles gambiae, Anopheles coluzzii, kdr, Togo