Use of buffy-coat smears in the diagnosis of septicaemia in children
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1983-12
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Abstract
Gram-stained buffy-coat smears from venous and capillary blood samples in 105 children suspected of septicaemia were examined for the presence of bacteria and the results compared with blood culture isolates. Gram-positive and Gram-negative bacteria were identified in 18 venous (44%) and 19 capillary (46%) buffy-coat preparations in 41 instances where bacterial organisms were isolated from the blood cultures. It is concluded that the examination of buffy-coat smears for bacteria in children suspected of septicaemia is a useful adjunct to blood cultures and, in areas where no facilities exist for culture of blood, may be a simple and rapid method of establishing the diagnosis of bacteraemia in suspected patients.
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Nkrumah, F. K., Neequaye, J., & Twum-Danso, K. (1983). Use of buffy-coat smears in the diagnosis of septicaemia in children. Annals of Tropical Paediatrics, 3(4), 193-196.