Comparison of Doppler and Oscillometric Methods of Assessing Ankle-Brachial Index in Non-diabetic Premenopausal Women in Ghana

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dc.contributor.authorAgyekum, J. A.
dc.contributor.authorOblitey, J.
dc.contributor.authorYeboah, K.
dc.date.accessioned2023-07-20T11:57:11Z
dc.date.available2023-07-20T11:57:11Z
dc.date.issued2023
dc.descriptionResearch Articleen_US
dc.description.abstractAbstract Introduction: Peripheral arterial disease (PAD) is a common cardiovascular disorder less commonly diagnosed in female patients. Peripheral arterial disease is objectively diagnosed using the ankle-brachial index (ABI), which can be measured using the “gold standard” Doppler method or the oscillometric method. The agreement between these 2 methods is less investigated in the sub-Saharan African population. Therefore, we compared the diagnostic characteristics of the oscillometric method of measuring ABI with the Doppler method in premenopausal female patients in Ghana. Methods: The ABI was measured in non-diabetic premenopausal women suspected of having PAD using the Doppler method with an 8 MHz handheld Doppler (LifeDop 250, Summit Doppler) and an oscillometric device (Vasera 1500N, Fukuda Denshi) in 160 patients (320 legs). Peripheral arterial disease was defined as an ABI <0.90 in at least one leg. Leg symptoms were assessed using the Edinburgh claudication questionnaire. Results: Leg pain on exertion was present in 101 patients screened with similar mean ABIs in the right and left legs. The prevalence of PAD as screened by the Doppler method was 25.7% (18.9%-33.4%) and that of the oscillometric method was 32.2% (24.9%-40.3%). In comparison with the Doppler method, the accuracy of the oscillometric method was 88.2%, and the sensitivity, specificity, positive predictive value, and negative predictive value were 89.7%, 87.6%, 71.4%, and 96.1%, respectively. The overall agreement between the Doppler and oscillometric methods was high, = 0.78 (0.62-0.91), P < .001, with an intraclass correlation of 0.89 (0.87-0.92, P < .001). In receiver-operating characteristic (ROC) curve analysis, the oscillometric method showed an area under the curve of 0.925 compared with the Doppler method in the diagnosis of PAD. Conclusion: In non-diabetic premenopausal women in our study, oscillometric ABI performed acceptably in the diagnosis of PAD when compared with Doppler ABI.en_US
dc.description.sponsorshipThe study was supported by the University of Ghana-Building a New Generation of Academics in Africa (BANGA-Africa) project with funding from the Carnegie Corporation of New Yorken_US
dc.identifier.otherhttps://doi.org/10.1177/15443167231179207
dc.identifier.urihttp://ugspace.ug.edu.gh:8080/handle/123456789/39594
dc.language.isoenen_US
dc.publisherSAGE Publications Ltden_US
dc.subjectPeripheral arterial diseaseen_US
dc.subjectAnkle-brachial indexen_US
dc.subjectDoppler ultrasounden_US
dc.subjectOscillometric blood pressureen_US
dc.subjectClaudicationen_US
dc.titleComparison of Doppler and Oscillometric Methods of Assessing Ankle-Brachial Index in Non-diabetic Premenopausal Women in Ghanaen_US
dc.typeArticleen_US

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