Helminth-induced ige and protection against allergic disorders

dc.contributor.authorHamid, F.
dc.contributor.authorAmoah, A.S.
dc.contributor.authorVan Ree, R.
dc.contributor.authorYazdanbakhsh, M.
dc.date.accessioned2018-11-13T16:34:45Z
dc.date.available2018-11-13T16:34:45Z
dc.date.issued2015-01
dc.description.abstractThe immune response against helminths and allergens is generally characterized by high levels of IgE and increased numbers of Th2 cells, eosinophils, and mast cells, yet the clinical outcome with respect to immediate hypersensitivity and inflammation is clearly not the same. High levels of IgE are seen to allergens during helminth infections; however, these IgE responses do not translate into allergy symptoms. This chapter summarizes the evidence of the association between helminth infections and allergic disorders. It discusses how helminth infection can lead to IgE cross-reactivity with allergens and how this IgE has poor biological activity. This information is important for developing new diagnostic methods and treatments for allergic disorders in low-to-middle-income countries. © Springer International Publishing Switzerland 2015.en_US
dc.identifier.otherhttps://doi.org/10.1007/978-3-319-13725-4_5
dc.identifier.urihttp://ugspace.ug.edu.gh/handle/123456789/25501
dc.language.isoenen_US
dc.publisherCurrent Topics in Microbiology and Immunologyen_US
dc.subjectSkin Prick Testen_US
dc.subjectHelminth Infectionen_US
dc.subjectMast Cell Degranulationen_US
dc.subjectAllergic Disorderen_US
dc.subjectSkin Prick Test Positivityen_US
dc.titleHelminth-induced ige and protection against allergic disordersen_US
dc.typeArticleen_US

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