Effects of a lipid-based nutrient supplement during pregnancy and lactation on maternal plasma fatty acid status and lipid profile: Results of two randomized controlled trials

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dc.contributor.authorOaks, B.M.
dc.contributor.authorYoung, R.R.
dc.contributor.authorAdu-Afarwuah, S.
dc.contributor.authorAshorn, U.
dc.contributor.authorJackson, K.H.
dc.contributor.authorLartey, A.
dc.contributor.authorMaleta, K.
dc.contributor.authorOkronipa, H.
dc.contributor.authorSadalaki, J.
dc.contributor.authorBaldiviez, L.M.
dc.contributor.authorShahab-Ferdows, S.
dc.contributor.authorAshorn, P.
dc.contributor.authorDewey, K.G.
dc.date.accessioned2019-02-08T10:02:10Z
dc.date.available2019-02-08T10:02:10Z
dc.date.issued2017-02
dc.description.abstractIt is unknown whether a novel small-quantity lipid-based nutrient supplement (SQ-LNS) containing alpha-linolenic (ALA) and linoleic acids impacts maternal plasma lipids and fatty acid status. We measured plasma fatty acids (wt%) and lipid concentrations at 36 wk gestation and breast milk fatty acids (wt%) at 6 months postpartum in a subsample of women enrolled in a randomized controlled trial studying the effects of SQ-LNS on birth outcomes and child growth. Women≤20 wk gestation in Ghana (n=1,320) and Malawi (n=1,391) were assigned to receive daily either: 1) iron-folic acid (pregnancy); 2) multiple micronutrients (pregnancy and lactation); or 3) SQ-LNS (pregnancy and lactation). At 36 wk, plasma ALA levels were higher in those receiving SQ-LNS. SQ-LNS increased breast milk ALA in Ghana but not Malawi. There was no effect on plasma lipids or other selected fatty acids. SQ-LNS may impact plasma and breast milk ALA levels depending on the population. © 2017 The Authorsen_US
dc.identifier.otherdoi: 10.1016/j.plefa.2017.01.007
dc.identifier.urihttp://ugspace.ug.edu.gh/handle/123456789/27360
dc.language.isoenen_US
dc.publisherProstaglandins Leukotrienes and Essential Fatty Acidsen_US
dc.subjectCholesterolen_US
dc.subjectLactationen_US
dc.subjectLipidsen_US
dc.subjectOmega-3 fatty acidsen_US
dc.subjectPregnancyen_US
dc.subjectSupplementationen_US
dc.titleEffects of a lipid-based nutrient supplement during pregnancy and lactation on maternal plasma fatty acid status and lipid profile: Results of two randomized controlled trialsen_US
dc.typeArticleen_US

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