Effects of a lipid-based nutrient supplement during pregnancy and lactation on maternal plasma fatty acid status and lipid profile: Results of two randomized controlled trials
dc.contributor.author | Oaks, B.M. | |
dc.contributor.author | Young, R.R. | |
dc.contributor.author | Adu-Afarwuah, S. | |
dc.contributor.author | Ashorn, U. | |
dc.contributor.author | Jackson, K.H. | |
dc.contributor.author | Lartey, A. | |
dc.contributor.author | Maleta, K. | |
dc.contributor.author | Okronipa, H. | |
dc.contributor.author | Sadalaki, J. | |
dc.contributor.author | Baldiviez, L.M. | |
dc.contributor.author | Shahab-Ferdows, S. | |
dc.contributor.author | Ashorn, P. | |
dc.contributor.author | Dewey, K.G. | |
dc.date.accessioned | 2019-02-08T10:02:10Z | |
dc.date.available | 2019-02-08T10:02:10Z | |
dc.date.issued | 2017-02 | |
dc.description.abstract | It is unknown whether a novel small-quantity lipid-based nutrient supplement (SQ-LNS) containing alpha-linolenic (ALA) and linoleic acids impacts maternal plasma lipids and fatty acid status. We measured plasma fatty acids (wt%) and lipid concentrations at 36 wk gestation and breast milk fatty acids (wt%) at 6 months postpartum in a subsample of women enrolled in a randomized controlled trial studying the effects of SQ-LNS on birth outcomes and child growth. Women≤20 wk gestation in Ghana (n=1,320) and Malawi (n=1,391) were assigned to receive daily either: 1) iron-folic acid (pregnancy); 2) multiple micronutrients (pregnancy and lactation); or 3) SQ-LNS (pregnancy and lactation). At 36 wk, plasma ALA levels were higher in those receiving SQ-LNS. SQ-LNS increased breast milk ALA in Ghana but not Malawi. There was no effect on plasma lipids or other selected fatty acids. SQ-LNS may impact plasma and breast milk ALA levels depending on the population. © 2017 The Authors | en_US |
dc.identifier.other | doi: 10.1016/j.plefa.2017.01.007 | |
dc.identifier.uri | http://ugspace.ug.edu.gh/handle/123456789/27360 | |
dc.language.iso | en | en_US |
dc.publisher | Prostaglandins Leukotrienes and Essential Fatty Acids | en_US |
dc.subject | Cholesterol | en_US |
dc.subject | Lactation | en_US |
dc.subject | Lipids | en_US |
dc.subject | Omega-3 fatty acids | en_US |
dc.subject | Pregnancy | en_US |
dc.subject | Supplementation | en_US |
dc.title | Effects of a lipid-based nutrient supplement during pregnancy and lactation on maternal plasma fatty acid status and lipid profile: Results of two randomized controlled trials | en_US |
dc.type | Article | en_US |
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