Urinary Tract Infections among Bladder Outlet Obstruction Patients in Accra, Ghana: Aetiology, Antibiotic Resistance, and Risk Factors
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Date
2018
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Diseases
Abstract
The aim of this study was to investigate urinary tract infections among patients with
Bladder Outlet Obstruction (BOO) at the Korle Bu Teaching Hospital (KBTH) in Accra, Ghana,
including the prevalence, risk factors, aetiological agents and their antibiogram. Urine specimens
were collected from 188 male patients presenting with BOO and cultured for bacteria. The bacterial
isolates were identified using standard microbiological methods and tested against a spectrum of
antimicrobial agents using the Kirby Bauer method. Demographic information and the clinical
history of study participants were also recorded. The prevalence of urinary tract infection among
the BOO patients was 76.6% and the main risk factor identified was catheterization (p < 0.0001).
A wide range of bacterial organisms was isolated from urine specimens and they were predominantly,
Enterobacteriaceae; Escherichia coli was the most frequent cause of bacteriuria (33.3%), followed by
Klebsiella (17.3%). Bacterial isolates were most resistant to Augmentin (97.8%) followed by tetracycline
(85.8%), nalidixic acid (82.8%) and ciprofloxacin (75%) while 93.6% were multi-drug resistant.
The highest susceptibility was observed with amikacin, which had a resistance prevalence of 4.4%
resistance. These findings have important implications in the treatment of urinary tract infections
among the BOO patients in Ghana.
Description
Research Article
Keywords
Bladder Outlet Obstruction, urinary tract infection, catheterization, E. coli