A multilateral effort to develop DNA vaccines against falciparum malaria.

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dc.contributor.authorKumar, S.
dc.contributor.authorEpstein, J.E.
dc.contributor.authorRichie, T.L.
dc.contributor.authorNkrumah, F.K.
dc.contributor.authorSoisson, L.
dc.contributor.authorCarucci, D.J.
dc.contributor.authorHoffman, S.L.
dc.date.accessioned2013-06-18T12:58:48Z
dc.date.accessioned2017-10-16T13:07:29Z
dc.date.available2013-06-18T12:58:48Z
dc.date.available2017-10-16T13:07:29Z
dc.date.issued2002
dc.description.abstractScientists from several organizations worldwide are working together to develop a multistage, multigene DNA-based vaccine against Plasmodium falciparum malaria. This collaborative vaccine development effort is named Multi-Stage DNA-based Malaria Vaccine Operation. An advisory board of international experts in vaccinology, malariology and field trials provides the scientific oversight to support the operation. This article discusses the rationale for the approach, underlying concepts and the pre-clinical development process, and provides a brief outline of the plans for the clinical testing of a multistage, multiantigen malaria vaccine based on DNA plasmid immunization technology.en_US
dc.description.sponsorshipThis work is supported by funds from the Naval Medical Research Center work units 62787A.870.F.A0010, 60000.000.000.A0062; and by funds from Malaria Vaccine Development Program, US. Agency for International Development work unit 604771N.0933.001.A0065.en_US
dc.identifier.citationKumar, S., Epstein, J. E., Richie, T. L., Nkrumah, F. K., Soisson, L., Carucci, D. J., & Hoffman, S. L. (2002). A multilateral effort to develop DNA vaccines against falciparum malaria. Trends in Parasitology, 18(3), 129-135.en_US
dc.identifier.urihttp://hinari-gw.who.int/whalecomwww.sciencedirect.com/whalecom0/science/article/pii/S1471492201022073
dc.identifier.urihttp://197.255.68.203/handle/123456789/3498
dc.language.isoenen_US
dc.publisherTrends in Parasitologyen_US
dc.subjectPlasmodium falciparumen_US
dc.subjectMalaria vaccineen_US
dc.subjectDNA vaccineen_US
dc.subjectPrime boosten_US
dc.subjectMulti-geneen_US
dc.subjectClinical trialen_US
dc.subjectParasitologyen_US
dc.subjectGeneticsen_US
dc.subjectPharmaceutical Scienceen_US
dc.titleA multilateral effort to develop DNA vaccines against falciparum malaria.en_US
dc.typeArticleen_US

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