Amodiaquine-induced dystonic reactions: Case reports and implications for policy change in Ghana

Abstract

Ten cases of amodiaquine-induced dystonic reactions observed in a single ward in Ghana's Premier Teaching Hospital, over a period of 4 years are presented. All the reactions resolved without sequalae on treatment with diazepam and benztropine. The importance of increased safety monitoring of amodiaquine as it is (in combination with artesunate) introduced as first line treatment for uncomplicated malaria in Ghana is highlighted. © 2005 - IOS Press and the authors. All rights reserved.