In vitro anti-plasmodial activity of three herbal remedies for malaria in Ghana: Adenia cissampeloides (Planch.) Harms., Termina liaivorensis A. Chev, and Elaeis guineensis Jacq

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dc.contributor.authorAnnan, K.
dc.contributor.authorSarpong, K.
dc.contributor.authorAsare, C.
dc.contributor.authorDickson, R.
dc.contributor.authorAmponsah, KI.
dc.contributor.authorGyan, B.
dc.contributor.authorOfori, M.
dc.contributor.authorGbedema, S.Y.
dc.date.accessioned2019-01-11T11:15:24Z
dc.date.available2019-01-11T11:15:24Z
dc.date.issued2012-10
dc.description.abstractBackground: Herbal remedies of Adenia cissampeloides, Terminalia ivorensis, and Elaeis guineensis among others have been used in Ghana for the treatment of various ailments including malaria. However, most of these remedies have not been scientifically investigated. Objective: This study, therefore, seeks to investigate the anti-plasmodial activity of these plants. Materials and Methods: The ethanolic extracts of A. cissampeloides stem, T. ivorensis stem bark, and E. guineensis leaves were tested for in vitro anti-plasmodial activity against chloroquine-resistant strains of Plasmodium falciparum. Thin blood films were used to assess the level of parasitemia and growth inhibition of the extracts. Results: The IC50 of A. cissampeloides, T. ivorensis, and E. guineensis were 8.521, 6.949, and 1.195 g/ml, respectively, compared to artesunate with IC50 of 0.031 g/ml. Conclusion: The result of this study appears to confirm the folkloric anti-malarial use these plants.en_US
dc.identifier.otherVolume 4, Issue 4, pp 225–229
dc.identifier.otherdoi: 10.4103/0974-8490.102270
dc.identifier.urihttp://ugspace.ug.edu.gh/handle/123456789/26764
dc.language.isoenen_US
dc.publisherPharmacognosy Researchen_US
dc.subjectAdenia cissampeloidesen_US
dc.subjectAnti-plasmodialen_US
dc.subjectElaeis guineensisen_US
dc.subjectHerbal remediesen_US
dc.subjectTerminalia ivorensisen_US
dc.titleIn vitro anti-plasmodial activity of three herbal remedies for malaria in Ghana: Adenia cissampeloides (Planch.) Harms., Termina liaivorensis A. Chev, and Elaeis guineensis Jacqen_US
dc.typeArticleen_US

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