The epidemiology of plasmodium falciparum malaria in two cameroonian villages: Simbok and etoa.
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Date
2000
Journal Title
Journal ISSN
Volume Title
Publisher
American Journal of Tropical Medicine and Hygiene
Abstract
In support of ongoing immunologic studies on immunity to Plasmodium falciparum, demographic, entomologic, parasitologic, and clinical studies were conducted in two Cameroonian villages located 3 km apart. Simbok (population = 907) has pools of water present year round that provide breeding sites for Anopheles gambiae, whereas Etoa (population = 485) has swampy areas that dry up annually in which A. funestus breed. Results showed that individuals in Simbok receive an estimated 1.9 and 1.2 infectious bites per night in the wet and dry season, respectively, whereas individuals in Etoa receive 2.4 and 0.4 infectious bites per night, respectively. Although transmission patterns differ, the rate of acquisition of immunity to malaria appears to be similar in both villages. A prevalence of 50-75% was found in children < 10 years old, variable levels in children 11-15 years old, and 31% in adults. Thus, as reported in other parts of Africa, individuals exposed to continuous transmission of P. falciparum slowly acquired significant, but not complete, immunity.
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Keywords
EMTREE medical terms: adolescent; adult; Anopheles gambiae; article; Cameroon; child; geographic distribution; human; insect bite; major clinical study; malaria falciparum; parasite transmission; Plasmodium falciparum; population research; prevalence, MeSH: Adolescent; Adult; Age Distribution; Aged; Animals; Anopheles; Cameroon; Child; Child, Preschool; Disease Vectors; Female; Humans; Infant; Infant, Newborn; Longitudinal Studies, Malaria, Falciparum; Male; Middle Aged; Plasmodium falciparum; Prevalence; Seasons Medline is the source for the MeSH terms of this document
Citation
Quakyi, I. A., Leke, R. G. F., Befidi-Mengue, R., Tsafack, M., Bomba-Nkolo, D., Manga, L., . . . Taylor, D. W. (2000). The epidemiology of plasmodium falciparum malaria in two cameroonian villages: Simbok and etoa. American Journal of Tropical Medicine and Hygiene,