Cardiopulmonary bypass surgery in sickle cell disease: An update

Abstract

We share our experience of two cases of successful mitral valve replacement and one tricuspid anuloplasty in patients with sic kle cell disease and a hi story of repeated sickling crises. This was done with cardiopulmonary bypass and moderate hypothermia. By avoiding acidosis. dehydration and hypoxia. successful cardiopulmonary bypass was effected without pre or intra-operative exchange transfusion.