Assessing CD4+ helper T-lymphocyte responses by lymphoproliferation
| dc.contributor.author | Quakyi, I.A. | |
| dc.contributor.author | Ahlers, J.D. | |
| dc.date.accessioned | 2013-06-21T13:20:52Z | |
| dc.date.accessioned | 2017-10-16T12:25:33Z | |
| dc.date.available | 2013-06-21T13:20:52Z | |
| dc.date.available | 2017-10-16T12:25:33Z | |
| dc.date.issued | 2002 | |
| dc.description.abstract | CD4+helper T cells play a central role in the development of malaria immune responses and a large number of epitopes from the sporozoite, sexual, and asexual stage of malaria proteins have been tabulated in both mice and humans (1-8). It is clear that the incorporation of antigenic determinants stimulating helper T cells is important for the induction of antibody responses (9-11) and cytotoxic T cell responses (12-15) stimulated by peptide or subunit vaccines. Helper T cells (Th) also may act as effectors themselves, by secreting cytokines that may significantly influence the clinical course following infection. | en_US |
| dc.identifier.citation | Quakyi, I. A., &Ahlers, J. D. (2002). Assessing CD4+ helper T-lymphocyte responses by lymphoproliferation. Methods in Molecular Medicine, 72, 369-383. | en_US |
| dc.identifier.uri | http://197.255.68.203/handle/123456789/3826 | |
| dc.language.iso | en | en_US |
| dc.publisher | Methods in Molecular Medicine | en_US |
| dc.subject | EMTREE drug terms: antigen; epitope; interleukin 2; malaria vaccine; peptide; recombinant vaccine | en_US |
| dc.subject | EMTREE medical terms: animal; article; Bagg albino mouse; biosynthesis; C3H mouse; C57BL mouse; helper cell; human; immunization; immunology; lymphocyte activation; methodology; mouse; mouse strain; Plasmodium falciparum; vaccination | en_US |
| dc.subject | MeSH: Animals; Antigens; Epitopes; Humans; Immunization; Interleukin-2; Lymphocyte Activation; Malaria Vaccines; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred Strains; Peptides; Plasmodium falciparum; T-Lymphocytes, Helper-Inducer; Vaccination; Vaccines, Synthetic | en_US |
| dc.title | Assessing CD4+ helper T-lymphocyte responses by lymphoproliferation | en_US |
| dc.type | Article | en_US |