Antibiotic susceptibility patterns of vibrio cholerae isolates in Ghana

Abstract

Strains of Vibrio cholerae isolated from stool cultures on TCBS from various hospitals in Ghana were identified using API 20E and serotyped with both monovalent and polyvalent sera. Susceptibility to 10 antimicrobial agents was tested by the disc diffusion method of Kirby-Bauer. Both Ogawa and Inaba strains were identified. Ninety-three percent (93%) of isolates were sensitive to tetracycline and nalidixic acid. All isolates were resistant to trimethoprim-sulphamethoxazole and colistin. Several strains showed intermediate sensitivity to chloramphenicol, ampicillin, and amoxycillinclavulanic acid. We conclude that tetracycline is still a useful drug for the treatment of cholera in Ghana.