Comparison of a new visual isothermal nucleic acid amplification test with PCR and skin snip analysis for diagnosis of onchocerciasis in humans
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Elsevier - Science Direct (Molecular & Biochemical Parasitology)
Abstract
Accurate, simple and affordable diagnostics are needed to detect Onchocerca volvulus infection in humans.
A newly developed colorimetric loop-mediated isothermal amplification (LAMP) assay was compared to
PCR and skin snip analysis for diagnosis of onchocerciasis. The robustness and simplicity of the assay
indicates that it may be a useful field tool for surveillance in endemic countries.
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Research Article
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Citation
A. Alhassan et al.(2016) Comparison of a new visual isothermal nucleic acid amplification test with PCR and skin snip analysis for diagnosis of onchocerciasis in humans. Molecular & Biochemical Parasitology 210 (2016) 10–12