Seasonal and pandemic influenza vaccine: Demand, supply and vaccine availability

Abstract

nfluenza has long been a compelling example of a global pandemic threat, but the annual disease burden has been relatively underappreciated, leading to missed opportu- nities for disease reduction and prevention. Convincing evidence of seasonal burden of disease in more settings and for a wider array of influenza outcomes will be the foundation of arguments for strengthening programs to control annual influenza and to reduce the threat of future pandemics (41,42). Countries with burden of disease estimates that have agreed to share data for the global estimate of influenza mortality and influenza-associated hospitalizations, as of April 2017: blue, morbidity estimates; brown, mortality estimates; green, morbidity and mortality estimates; white, data not available. ...