In vitro antibacterial activity of PEG formulations of crude extracts of cleome viscosa, Tamarindus indica and Euphorbia hirta

Simple item page
dc.contributor.authorDonkor, A.- M.
dc.contributor.authorOduro-Mensah, D.
dc.contributor.authorKonona-Ang Patience, M.
dc.date.accessioned2019-04-29T16:56:49Z
dc.date.available2019-04-29T16:56:49Z
dc.date.issued2016
dc.description.abstractBackground: In rural settings, some medicinal plant extracts serve as alternative agents for wound treatment. Topical application of such extracts would be greatly enhanced if formulations such as ointment-based preparations were available. Methodology: This study sought to investigate the antibacterial activity of polyethylene glycol ointment formulations of crude extracts of Cleome viscosa, Tamarindus indica and Euphorbia hirta against Pseudomonas aeruginosa and Escherichia coli. Antibacterial activities were studied at concentrations of 25, 50, 100 and 200 µg mL-1 for the test extracts and 25, 50, 100 and 200 µg g-1 for the polyethylene glycol formulations. Results: Generally, the crude extracts as well as their formulations showed increasing levels of inhibition with increasing concentrations. Polyethylene glycol formulations of Euphobia hirta and Cleome viscosa crude extracts exhibited significant potencies against growth of Pseudomonas aeruginosa and Escherichia coli. Conclusion: Both Euphobia hirta and Cleome viscosa crude extract-polyethylene glycol ointments have therefore emerged as potentially effective formulations against Escherichia coli and P. aeruginosa wound infections. © 2016 Addai-Mensah Donkor et al.en_US
dc.identifier.citationAddai-Mensah Donkor, Daniel Oduro-Mensah and M. Konona-Ang Patience, 2016. In vitro antibacterial activity of peg formulations of crude extracts of Cleome viscosa, Tamarindus indica and Euphorbia hirta. Res. J. Microbiol., 11: 202-207en_US
dc.identifier.issn18164935
dc.identifier.otherdoi.10.3923/jm.2016.202.207
dc.identifier.othervol. 11 (6): 202-207
dc.identifier.urihttp://ugspace.ug.edu.gh/handle/123456789/29654
dc.language.isoenen_US
dc.publisherAcademic Journals Inc.en_US
dc.subjectE. colien_US
dc.subjectOintmenten_US
dc.subjectP. aeruginosaen_US
dc.subjectPlant extracten_US
dc.subjectPolyethylene glycolen_US
dc.titleIn vitro antibacterial activity of PEG formulations of crude extracts of cleome viscosa, Tamarindus indica and Euphorbia hirtaen_US
dc.typeArticleen_US

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
In vitro antibacterial activity of PEG formulations of crude extracts of cleome viscosa, Tamarindus indica and Euphorbia hirta.pdf
Size:
250.53 KB
Format:
Adobe Portable Document Format
Description:
"Main Article"
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.6 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

Department of Biochemistry, Cell and Molecular Biology