Culture and sensitivity of mycobacterial isolates from cases of pulmonary tuberculosis classified as treatment failures in a teaching hospital
| dc.contributor.author | Newman, M.J. | |
| dc.contributor.author | Addo, K.K. | |
| dc.contributor.author | Aboagye, S. | |
| dc.contributor.author | Bonsu, F.A. | |
| dc.contributor.author | Caulley, P. | |
| dc.contributor.author | Hesse, I.F. | |
| dc.contributor.author | Neequaye, A.R. | |
| dc.contributor.author | Kudzawu, S. | |
| dc.date.accessioned | 2012-05-03T17:01:00Z | |
| dc.date.accessioned | 2017-10-16T13:09:18Z | |
| dc.date.available | 2012-05-03T17:01:00Z | |
| dc.date.available | 2017-10-16T13:09:18Z | |
| dc.date.issued | 2007 | |
| dc.description.abstract | The level of drug resistance in mycobacterial isolates from previously treated cases in Ghana is not known although drug resistant tuberculosis threatens efforts to control the disease. Objective: To identify and determine the susceptibility of mycobacterial isolates from tuberculosis cases with clinical treatment failure. Methods: This prospective survey was undertaken at the Chest Clinic of Korle Bu Teaching Hospital in Accra, Ghana. The participants were twenty-eight cases referred to the hospital with clinical treatment failure. Two sputum specimens from each case were stained by Ziehl-Neelsen method, cultured, identified and sensitivity tests performed by the proportion method. Results: Eighteen isolates of mycobacteria were identified from 28 failed treatment cases. Five were atypical mycobacteria. Approximately fifty percent (13/28) of cases had Mycobacterium tuberculosis, 5(18%) had atypical mycobacteria, 7(25%) had pure fungal growth and 3(11% 8) had no growth. Fifteen isolates were resistant to two or more drugs, of which 6 were resistant to all four drugs tested. Conclusion: Continuous drug resistance monitoring must be instituted as part of the tuberculosis control programme. | en_US |
| dc.identifier.uri | http://197.255.68.203/handle/123456789/1036 | |
| dc.language.iso | en | en_US |
| dc.publisher | West African Journal of Medicine 26(2): 131-3 | en_US |
| dc.title | Culture and sensitivity of mycobacterial isolates from cases of pulmonary tuberculosis classified as treatment failures in a teaching hospital | en_US |
| dc.type | Article | en_US |