Factors associated with malaria vaccine uptake in Sunyani Municipality, Ghana

Abstract

Background: Malaria continues to be a major disease of public health concern afecting several million people worldwide. The World Health Organization (WHO) started a pilot study on a malaria vaccine (RTS,S) in Ghana and two other countries in 2019. This study aimed at assessing the factors associated with uptake of the vaccine in the Sunyani Municipality of Ghana. Methods: The study was a cross-sectional study employing a quantitative approach. Stratifed sampling technique was used to select respondents. A structured questionnaire was administered to parents/caregivers with children eligible to have taken the frst three doses of the malaria vaccine by December 2019. The Child Welfare Clinic (CWC) cards of the eligible children were also inspected. Ordinal logistic regression analysis was done to determine the asso ciation between the independent variables and full vaccine uptake. Results: Uptake of RTS,S 1 was 94.1%. However, this fgure reduced to 90.6% for RTS,S 2, and 78.1% for RTS,S 3. Chil dren with a parent who had been educated up to the tertiary level had 4.72 (AOR: 4.72, 95% CI 1.27–17.55) increased odds of full uptake as compared to those who completed secondary education. Parents whose children had expe rienced fever as an adverse reaction were more likely to send their children for the malaria vaccine as compared to those whose children had ever sufered abscess as an adverse reaction (AOR: 2.27, 95% CI 1.13–5.10). Children with parents who thought vaccines were becoming too many for children had 71% (AOR: 0.29, 95% CI 0.14–0.61) reduced odds of full uptake as compared to those who thought otherwise. Conclusion: Uptake of RTS,S 1 and RTS,S 2 in Sunyani Municipality meets the WHO’s target coverage for vaccines, however, RTS,S 3 uptake does not. Furthermore, there is a growing perception amongst parents/caregivers that vac cines are becoming too many for children which negatively afects uptake.