Formal Security Guarantees for Blockchain-Based Patient Digital Twins in Remote Health Monitoring Systems
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IEEE Journal of the Electron Devices Society
Abstract
Remote health monitoring systems can be imple
mented effectively using Patient Digital Twins (PDTs) to support
continuous patient monitoring, predictive analytics, personalized
treatment planning, and clinical decision support. However, the
large-scale aggregation, storage, and exchange of sensitive health
data expose PDT systems to significant security and privacy risks,
including unauthorized access, data tampering, identity forgery,
and unauthorised disclosure of patient information. Although
blockchain technology has been proposed as a mechanism for
enhancing trust and auditability in healthcare data-sharing envi
ronments, existing blockchain-based PDT frameworks primarily
focus on system architecture and functionality, with limited
formal security guarantees. The objective of this paper is to
determine whether blockchain-based PDTs can provide formally
provable guarantees of confidentiality, integrity, access control
correctness, revocation security, auditability, and non-repudiation
in remote health monitoring environments. To achieve this
objective, we develop a blockchain-enabled PDT architecture
that combines cryptographic access control, digital signatures,
smart contracts, and decentralized off-chain storage within a
unified security framework. The security analysis demonstrates
that the proposed framework achieves the defined security prop
erties against probabilistic polynomial-time adversaries under the
stated cryptographic assumptions. Furthermore, an experimental
implementation using Hyperledger Fabric and the InterPlanetary
File System (IPFS) evaluates the computational overhead, trans
action latency, storage efficiency, and scalability of the architec
ture with experimental results indicating that the framework
introduces modest cryptographic overhead while maintaining
practical transaction latency and near-linear throughput scal
ability under increasing workloads.
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Research Article
Citation
Amofa, S., Adu-Manu, K. S., Adjetey, C., & Mensah, S. (2026). Formal Security Guarantees for Blockchain-Based Patient Digital Twins in Remote Health Monitoring Systems. IEEE Journal of the Electron Devices Society.
