Insights into Pneumococcal Pathogenesis and Antibiotic Resistance
Date
2014
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Advances in Microbiology
Abstract
Since its discovery in 1891, the pneumococcus has been one of the most extensively studied mi crobes, and was involved in several historical findings such as the discovery of genetic material
that was later shown to be DNA. The pneumococcus is part of the normal bacterial flora of the na sopharynx, but can on occasions progress to sterile sites of the body and cause invasive diseases.
There are about one million new invasive pneumococcal infections every year, majority of which
occur in the developing world where children <5 years are most affected. The burden of pneumo coccal disease is further heightened by the increasing prevalence of multidrug resistance of the
organism. The pneumococcus remains a pathogen of immense public health significance and un derstanding its biology, particularly the pathogenesis and antibiotic resistance is crucial to con trolling pneumococcal disease.
Description
Research Article
Keywords
Pneumococcus, Antibiotic Resistance, Virulence, Penicillin