Urinary Tract Infection and Associated Factors among Pregnant Women Receiving Antenatal Care at a Primary Health Care Facility in the Northern Region of Ghana
Loading...
Date
2023
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Hindawi
Abstract
Urinary tract infection (UTI) is frequently encountered during pregnancy and is associated with adverse maternal, fetal, and
neonatal efects. However, very little information is available on the prevalence of UTI among pregnant women in the northern
part of Ghana, a region with a high birth rate. Tis study employed a cross-sectional analysis of the prevalence, antimicrobial
profle, and risk factors associated with UTI in 560 pregnant women attending primary care for antenatal check-ups. Sociodemographic obstetrical history and personal hygiene information were obtained using a well-structured questionnaire. Afterward, clean catch mid-stream urine samples were collected from all participants and subjected to routine microscopy
examination and culture. Of 560 pregnant women, 223 cases (39.8%) were positive for UTI. Tere was a statistically signifcant
association between sociodemographic, obstetric, and personal hygiene variables and UTI (p < 0.0001). Escherichia coli (27.8%)
was the commonest bacterial isolate followed by CoNS (13.5%) and Proteus species (12.6%). Tese isolates exhibited greater
resistance to ampicillin (70.1–97.3%) and cotrimoxazole (48.1–89.7%) but were fairly susceptible to gentamycin and ciprofoxacin.
Gram-negative resistance to meropenem was up to 25.0%, and Gram positives resistance to cefoxitin and vancomycin was up to
33.3% and 71.4% respectively. Te current fndings extend our knowledge of the high frequency of UTIs and associated risk factors
in pregnant women with E. Coli being the predominant and usual isolate. Variation existed in the resistance pattern of isolates to
various drugs, underscoring the need to perform urine culture and susceptibility before treatment.
Description
Research Aritcle
Keywords
Urinary tract infection, Northern Region, Ghana, Pregnant Women, Antenatal Care