Total antioxidant status in non-insulin-dependent diabetes mellitus patients in Ghana.

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dc.contributor.authorDosoo, D.K.
dc.contributor.authorRana, S.V.
dc.contributor.authorOffe-Amoyaw, K.
dc.contributor.authorTete-Donkor, D.
dc.contributor.authorMaddy, S.Q.
dc.date.accessioned2019-02-26T15:08:11Z
dc.date.available2019-02-26T15:08:11Z
dc.date.issued2007-07
dc.description.abstractTotal antioxidant status (TAS) was measured in thirty-five (35) non-insulin-dependent diabetes mellitus (NIDDM) patients aged 40 to 65 (mean +/- SE 49.6 +/- 1.0) years. Patients were on diet and oral hypoglycaemic drug (Daonil) therapy with fasting plasma glucose (FPG) >7.8mmol/l. Similar measurements were carried out in thirty-four apparently healthy individuals within the same age range (mean + SE 46.3 +/- 1.1 years) and FPG <6.4 mmol/L. FPG was measured by glucose oxidase method and TAS by colorimetric method. Comparing the two groups, TAS was significantly reduced in the NIDDM patients (p<0.001). An inverse correlation between FPG and TAS suggests the existence of lower antioxidant defence in uncontrolled NIDDM. A good control of FPG accompanied with antioxidant therapy could help reduce free radical activity and minimise complications associated with increased free radical activity in diabetic patients.en_US
dc.identifier.otherVol. 10(2): pp 126-9
dc.identifier.urihttp://ugspace.ug.edu.gh/handle/123456789/28389
dc.language.isoenen_US
dc.publisherWest African journal of medicineen_US
dc.subjectAntioxidanten_US
dc.subjectNon-insulin-dependent diabetesen_US
dc.subjectDiabetesen_US
dc.subjectMellitus patientsen_US
dc.titleTotal antioxidant status in non-insulin-dependent diabetes mellitus patients in Ghana.en_US
dc.typeArticleen_US

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