The Pan African Vivax and Ovale Network (PAVON): Refocusing on Plasmodium vivax, ovale and asymptomatic malaria in sub-Saharan Africa
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Date
2021
Journal Title
Journal ISSN
Volume Title
Publisher
Parasitology International
Abstract
The recent World Malaria report shows that progress in malaria elimination has stalled. Current data acquisition
by NMCPs depend on passive case detection and clinical reports focused mainly on Plasmodium falciparum (Pf). In
recent times, several countries in sub-Saharan Africa have reported cases of Plasmodium vivax (Pv) with a
considerable number being Duffy negative. The burden of Pv and Plasmodium ovale (Po) appear to be more than
acknowledged. Similarly, the contribution of asymptomatic malaria in transmission is hardly considered by
NMCPs in Africa. Inclusion of these as targets in malaria elimination agenda is necessary to achieve elimination
goal, as these harbor hypnozoites.
The Pan African Vivax and Ovale Network (PAVON) is a new consortium of African Scientists working in
Africa on the transmission profile of Pv and Po. The group collaborates with African NMCPs to train in Plasmodium
molecular diagnostics, microscopy, and interpretation of molecular data from active surveys to translate
into policy. Details of the mission, rational and modus operandi of the group are outlined.
Description
Research Article
Keywords
PAVON, Plasmodium vivax transmission, Plasmodium ovale, Asymptomatic transmission, Sub-Saharan Africa