Factors Associated with Ruptured Ectopic Pregnancy: A 10-Year Review at a District Hospital in Ghana
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Date
2022
Journal Title
Journal ISSN
Volume Title
Publisher
Hindawi
Abstract
Background. Approximately 1–2% of all pregnancies are ectopic. Despite a decline in ectopic pregnancy-related mortality, there is
still a paucity of information on the factors associated with clinical presentation and outcomes in Sub-Saharan Africa which is
essential in determining the most appropriate treatment modalities. Methods. We performed a ten-year retrospective chart review
of cases of ectopic pregnancies managed at the Lekma hospital and assessed them for peculiar risk factors, clinical presentation,
and outcomes. Associations between patients’ sociodemographic characteristics, clinical presentation, and treatment outcome
were evaluated using multiple logistic regression and reported as adjusted odds ratios (AOR). ,e confidence interval (CI) was set
at 95%, and a p value <0.05 were considered significant. Results. Over the ten-year period, there were 115 ectopic pregnancies and
14,450 deliveries (7.9/1,000).,e mean age ± standard deviation of the 115 patients was 27.61 ± 5.56. More than half of the patients
were single (59/115, 51.3%). ,e majority (71.3%) of the patients presented with a ruptured ectopic pregnancy. After adjusting for
covariates, the odds of an ectopic pregnancy presenting as ruptured among single patients was 2.63 times higher than that of
married patients (AOR =3.63, 95% CI: 1.33–9.93, p = 0.01). Ectopic pregnancies located in the isthmic region of the tube had a
77% lower odds of presenting as ruptured than those located in the ampullary region (AOR = 0.23, 95% CI: 0.07–0.74, p = 0.01).
,e odds of rupturing were 1.69 times increased for every additional week after the missed period (AOR = 2.69, 95% CI: 1.56–4.64,
p < 0.01). No mortalities were reported as a result of an ectopic pregnancy. Conclusion. Most of the cases of ectopic pregnancy
presented ruptured. Marital status and period of amenorrhoea were significantly associated with rupture.
Description
Research Article