Randomized comparison of 3 types of micronutrient supplements for home fortification of complementary foods in Ghana: Effects on growth and motor development
dc.contributor.author | Adu-Afarwuah, S. | |
dc.contributor.author | Lartey, A. | |
dc.contributor.author | Brown, K.H. | |
dc.contributor.author | Zlotkin, S. | |
dc.contributor.author | Briend, A. | |
dc.contributor.author | Dewey, K.G. | |
dc.date.accessioned | 2019-04-05T09:31:41Z | |
dc.date.available | 2019-04-05T09:31:41Z | |
dc.date.issued | 2007-09 | |
dc.description.abstract | Background: The low micronutrient content of complementary foods is associated with growth faltering in many populations. A potential low-cost solution is the home fortification of complementary foods with Sprinkles (SP) powder, crushable Nutritabs (NT) tablets, or energy-dense (108 kcal/d), fat-based Nutributter (NB). Objective: The objective was to test the hypothesis that multiple micronutrients added to home-prepared complementary foods would increase growth and that the effect would be greatest in the presence of added energy from fat. Design: We randomly assigned 313 Ghanaian infants to receive SP, NT, or NB containing 6, 16, and 19 vitamins and minerals, respectively, daily from 6 to 12 mo of age. We assessed anthropometric status at 6, 9, and 12 mo; micronutrient status at 6 and 12 mo; motor development at 12 mo; and morbidity weekly. Infants (n = 96) not randomly selected for the intervention (nonintervention; NI) were assessed at 12 mo. Results: The groups did not differ significantly at baseline, except that the NB group had a higher proportion of boys and weighed slightly more. The dropout rate (15/313) was low. At 12 mo, after control for initial size, the NB group had a significantly greater weight-for-age z score (WAZ) (-0.49 ± 0.54) and length-for-age z score (LAZ) (-0.20 ± 0.54) than did the NT group (WAZ: -0.67 ± 0.54; LAZ: -0.39 ± 0.54) and the NT and SP groups combined (WAZ:-0.65 ± 0.54; LAZ: -0.38 ± 0.54); the difference with the NI group (WAZ: -0.74 ± 1.1; LAZ: -0.40 ± 1.0) was not significant. A lower percentage of the NI infants (25%) than of the intervention groups (SP: 39%; NT: 36%; NB: 49%) could walk independently by 12 mo. Conclusion: All 3 supplements had positive effects on motor milestone acquisition by 12 mo compared with no intervention, but only NB affected growth. | en_US |
dc.identifier.other | DOI: 10.1093/ajcn/86.2.412 | |
dc.identifier.other | Vol.86(2): pp 412-20 | |
dc.identifier.uri | http://ugspace.ug.edu.gh/handle/123456789/29055 | |
dc.language.iso | en | en_US |
dc.publisher | American Journal of Clinical Nutrition | en_US |
dc.subject | Ghana | en_US |
dc.subject | Home fortification | en_US |
dc.subject | Infant growth | en_US |
dc.subject | Motor development | en_US |
dc.subject | Multiple micronutrient supplements | en_US |
dc.title | Randomized comparison of 3 types of micronutrient supplements for home fortification of complementary foods in Ghana: Effects on growth and motor development | en_US |
dc.type | Article | en_US |
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