Dyslipidaemia among Ghanaian migrants in three European countries and their compatriots in rural and urban Ghana: The RODAM study

dc.contributor.authorvan der Linden, E.
dc.contributor.authorMeeks, K.
dc.contributor.authorBeune, E.
dc.contributor.authorde-Graft Aikins, A.
dc.contributor.authorAddo, J.
dc.contributor.authorOwusu-Dabo, E.
dc.contributor.authorMockenhaupt, F.P.
dc.contributor.authorBahendeka, S.et.al.
dc.date.accessioned2019-05-28T12:41:38Z
dc.date.available2019-05-28T12:41:38Z
dc.date.issued2019-05
dc.description.abstractBackground and aims African populations have a favourable lipid profile compared to European populations. However, the extent to which they differ between rural and urban settings in Africa and upon migration to Europe is unknown. We assessed the lipid profiles of Ghanaians living in rural- and urban-Ghana and Ghanaian migrants living in three European countries. Methods We used data from a multi-centre, cross-sectional study among Ghanaian adults residing in rural- and urban-Ghana and London, Amsterdam and Berlin (n = 5482). Dyslipidaemias were defined using the 2012 European Guidelines on Cardiovascular Prevention. Comparisons between groups were made using age-standardised prevalence and prevalence ratios (PRs) with adjustments for important covariates. Results In both sexes, the age-standardised prevalence of high total cholesterol (TC) and LDL-cholesterol (LDL-C) was lower in rural- than in urban-Ghana and Ghanaian migrants in Europe. Adjusted PRs of high TC and LDL-C were higher in urban-Ghana (TC PR = 2.15, 95%confidence interval 1.69–2.73) and Ghanaian migrant men (TC PR = 2.03 (1.56–2.63)) compared to rural-Ghana, but there was no difference between rural- and Ghanaian migrant women (TC PR = 1.01 (0.84–1.22)). High triglycerides levels were as prevalent in rural-Ghana (11.6%) as in urban-Ghana (12.8%), but were less prevalent in Ghanaian migrant women (2.0%). In both sexes, low HDL-cholesterol was most prevalent in rural-Ghana (50.1%) and least prevalent in Europe (12.9%). Conclusion The lipid profile varied among ethnically homogeneous African populations living in different geographical locations in Africa and Europe. Additional research is needed to identify factors driving these differential risks to assist prevention efforts.en_US
dc.identifier.otherhttps://doi.org/10.1016/j.atherosclerosis.2019.02.030
dc.identifier.otherVolume 284,Pages 83-91
dc.identifier.urihttp://ugspace.ug.edu.gh/handle/123456789/30361
dc.language.isoenen_US
dc.publisherAtherosclerosisen_US
dc.subjectDyslipidaemiaen_US
dc.subjectSub-Saharan Africaen_US
dc.subjectGhanaen_US
dc.subjectMigranten_US
dc.subjectEuropeen_US
dc.subjectRODAM studyen_US
dc.titleDyslipidaemia among Ghanaian migrants in three European countries and their compatriots in rural and urban Ghana: The RODAM studyen_US
dc.typeArticleen_US

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