Biochemical Pharmacology
| dc.contributor.author | Reddy, G.R. | |
| dc.contributor.author | Ueda, N | |
| dc.contributor.author | Hada, T | |
| dc.contributor.author | Sackeyfio, A.C. | |
| dc.contributor.author | Yamamoto, S | |
| dc.contributor.author | Hano, Y | |
| dc.contributor.author | Nomura, T | |
| dc.date.accessioned | 2013-06-21T13:41:54Z | |
| dc.date.accessioned | 2017-10-16T11:43:36Z | |
| dc.date.available | 2013-06-21T13:41:54Z | |
| dc.date.available | 2017-10-16T11:43:36Z | |
| dc.date.issued | 1991 | |
| dc.description.abstract | Several naturally occurring prenylflavones were tested for their inhibitory actions on arachidonate 5-lipoxygenase purified from porcine leukocytes. Of the compounds tested, artonin E (5'-hydroxymorusin) exhibited the most potent inhibition on arachidonate 5-lipoxygenase (IC50 = 0.36 microM). Arachidonate 12-lipoxygenase purified from porcine leukocytes and human platelets, 15-lipoxygenase from rabbit reticulocytes and fatty acid cyclooxygenase from bovine vesicular glands were inhibited by the compound only at higher concentrations (IC50 = 2.3, 11, 5.2 and 2.5 microM, respectively). | en_US |
| dc.identifier.citation | Reddy, G. R., Ueda, N., Hada, T., Sackeyfio, A. C., Yamamoto, S., Hano, Y., . . . Nomura, T. (1991). A prenylflavone, artonin E, as arachidonate 5-lipoxygenase inhibitor. Biochemical Pharmacology, 41(1), 115-118. | en_US |
| dc.identifier.uri | http://197.255.68.203/handle/123456789/3838 | |
| dc.language.iso | en | en_US |
| dc.publisher | Biochemical Pharmacology | en_US |
| dc.title | Biochemical Pharmacology | en_US |
| dc.type | Article | en_US |