Identification of Amino Acid Substitutions Within the VP7 Genes of G2 Rotavirus Strains in Ghana
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Date
2018-11
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Publisher
The Pediatric infectious disease journal
Abstract
We used the dideoxynucleotide chain termination method to determine the strains of nine non-typeable rotavirus enzyme immunoassay–positive samples, which were identified as G2. We detected nucleotide changes in the primer-binding region and amino acid substitutions within the VP7 protein of the G2 rotavirus strains. Genotyping primers need to be updated regularly.