Fibrin-degradation products in cerebral malaria.

Abstract

The serum concentrations of fibrin-degradation products (F.D.P.) were estimated in twenty-five patients with falciparum malaria. Cerebral features were present in nine of the seventeen Ghanaian children studied in Accra, and in one of eight adults observed in England. High levels of F.D.P. were found in all ten patients with cerebral malaria; in the fifteen patients without cerebral symptoms, F.D.P. levels were usually normal.