Browsing by Author "Clegg-Lamptey, J. N. A."
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Item Breast cancer risk in patients with breast pain in Accra, Ghana(East African Medical Journal 84(5): 215-8, 2007) Clegg-Lamptey, J. N. A.; Edusa, C.; Ohene-Oti, N.; Tagoe, J.Item Endoscopic evaluation of the colorectum in patients presenting with haematochezia at Korle-Bu Teaching Hospital, Accra(Ghana Medical Journal 42(1): 33-7, 2008) Dakubo, J. C. B.; Kumoji, R.; Naader, S. B.; Clegg-Lamptey, J. N. A.Background: Colorectal endoscopy is the gold stan- dard investigation of the large bowel in patients with rectal bleeding and is employed as a means of secon- dary prevention of colorectal cancer. Aim: To determine the frequency of benign lesions and carcinomas in patients who underwent colorectal endo- scopy because of rectal bleeding and to evaluate the role of endoscopy in secondary prevention of colorectal carcinoma in our centre. Method: A retrospective study was undertaken on pa- tients who underwent colorectal endoscopy between January 1995 and December 2000 for rectal bleeding. Results: Five hundred and ninety six (596) patients were studied. Males were 403 and females 93, mean age 50.9 (SD 7.07). Three hundred and ten patients (52%) had rigid proctosigmoidoscopy, flexible sigmoi- doscopy 105 (17.6%) and colonoscopy 181 (30.4%). Of those who had colonoscopy complete examination of the colon was achieved in 55 patients (30.4%). Those in whom colonoscopy was incomplete had dou- ble contrast barium enema. Haemorrhoids were the commonest disease diagnosed, 316 patients (53%). Co- lorectal carcinoma 39 patients (6.7%), non-specific co- litis 34 patients (5.7%), diverticular disease 27 patients (4.5%) and adenomatous polyps 17 patients (2.9%) were the next common disease. Less common condi- tions were ulcerative colitis, rectal schistosomiasis and angiodysplasia. In 125 patients (21.0) the cause of bleeding could not be found. Conclusion: An appreciable number of the patients with rectal bleeding had serious pathology that was di- agnosed early by endoscopy confirming the important role of endoscopy in secondary prevention of colorectal carcinoma. The low success rate of full colonoscopy underscores the need for training in this procedure.Item Hormone receptor and her expression in breast cancers among sub-Saharan African women(Ghana Medical Journal 14(5): 510-1, 2008) Clegg-Lamptey, J. N. A.; Yarney, J.; Vanderpuye, V.Item A study of breast cancer in Korle Bu Teaching Hospital(Assessing the impact of health education . Ghana Medical Journal 41(2): 72-77, 2007) Clegg-Lamptey, J. N. A.; Hodasi, W. M.Introduction: Many patients with breast cancer report late with advanced disease. It is not known if recent breast awareness education programmes have led to a change in this trend at the Korle Bu Teaching hospital (KBTH). Method: A prospective study of the characteristics of breast cancer patients seen by a surgical unit at KBTH over a three year period. Results: There were 158 patients, 156 females and 2 males. The age group most commonly affected was 40-49. The upper outer quadrant of the breast was affected in 67/158 (42.4%) and all quadrants affected in 29/158 (18.4%). Ninety one (57.6%) had Stage III – IV disease and the average duration of symptoms was 10 months. Average tumour size was 6cm x 7cm. Diagnosis was by triple assessment with Fine needle aspiration cytology the most frequently used pathological investigation. Invasive ductal carcinoma was the commonest pathological type (115/134). Eighty three (52.5%) had mastectomy and 12 (7.6%) had wide local excision. Neoadjuvant chemotherapy was given to 77/123 (62.6%), 5 of whom had complete pathological response. Fifty five (34.8%) were lost to follow up: 20 before treatment commenced, 15 during or after neoadjuvant chemotherapy and 14 after treatment. Eleven developed lymphoedema. There were 42 metastatic events affecting 35 patients during follow-up, including pleura (11), brain (10) and lungs (9). Conclusions: Breast cancer continues to affect a young population and patients still present late with advanced disease. Education needs to be intensified, but research into the reasons for late presentation will help address the reasons/ misconceptions responsible for this state of affairs.Item Typhoid ileal perforation in Ghana: A five-year retrospective study(Tropical Doctor 37 (4): 231-3, 2007) Clegg-Lamptey, J. N. A.; Dakubo, J. C. B.; Hodasi, W. M.Item Upper Gastrointestinal edoscopy at the Korle-Bu Teaching Hospital(Ghana Medical Journal 41{1): 12-16, 2007) Aduful, H.K.; Naaeder, S. B.; Darko, R.; Baako, B. N.; Clegg-Lamptey, J. N. A.; Nkrumah, K. N.; Adu-Aryee, N. A.; M